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Job DescriptionP00519
Confidence100.00%DateSat Jun 16 10:22:56 BST 2012
Rank110Aligned Residues247
% Identity24%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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Query Sequence  RTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTME. . . . VEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYII
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Template Sequence  PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFG
Template Known Secondary structure  GGG
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TT
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   7980.........90.........100.........110.........120.........130.........140.........150........
 
   315....320.........330.........340.........350.........360.........370.........380.........390....
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Query Sequence  TEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYT
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Template Sequence  LSYAKNGELLKYIRKIGS. . FDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . .
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   159160.........170...... ...180.........190.........200.........210.........220.........230
 
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Query Sequence  AHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRA
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Template Sequence  . . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVEK
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GGG

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   242.......250.........260.........270....... ..280.........290........ .300.........310.....
 
   475....480.........490.........
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Query Sequence  CWQWNPSDRPSFAEIHQAFETMFQE
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Template Sequence  LLVLDATKRLGCEEMEGYGPLKAHP
Template Known Secondary structure  TS
SSTTSSTTSGGGTTSG
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   316...320.........330.........340
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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