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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank93Aligned Residues254
% Identity37%Templatec3sxrA_
PDB info PDB header:transferase/transferase inhibitorChain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   363......370.........380.........390.........400.........410.........420.........430......... 440.
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Query Sequence  VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EA
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Template Sequence  MELKREEITL. LKELGSVVKLGKW. . . . . . . KGQYDVAVKMIKEGSMSE. . . DEFFQEAQTMMKLSHPKLVKFYGVCSKE
Template Known Secondary structure 
B

GGG.

.......TTT
BTTB
...S

TTB


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   410......... 420.........430.. .......440.........450 .........460.........470........
 
   442.......450.........460..... ....470.........480.........490.........500.........510.........520
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Query Sequence  ESWMLVMEMAELGPLNKYLQQNRH. VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALR
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Template Sequence  YPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVL
Template Known Secondary structure  SS

TT
BGGGS
TTTT
SGGG
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TTT

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   483......490.........500.........510.........520.........530.........540.........550.........560..
 
   521........530.........540.........550.........560.........570.........580.........590.........600
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Query Sequence  ADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
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Template Sequence  DDQYVSSVGTKFPVK. . WSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKMPYDLYTNSEVVLKVSQGHRLYRPHLASDT
Template Known Secondary structure  TT


S



GG..G

STTTTS

TTTT

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   563......570....... ..580.........590.........600.........610.........620.........630.........640
 
   601........610.........620.........
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Query Sequence  MYDLMNLCWTYDVENRPGFAAVELRLRNY
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Template Sequence  IYQIMYSCWHELPEKRPTFQQLLSSIEPL
Template Known Secondary structure  TT
SSGGGS

GGG
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   641........650.........660.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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