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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank182Aligned Residues232
% Identity26%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   371........380.........390.........400.........410.........420.........430.........440... ......
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Query Sequence  TLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES. WMLVME
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Template Sequence  FEYLKLLGKGTFGKVILVKEKATG. . RYYAMKILKKE. . . . . . . . . VIVANRVLQNSRHPFLTALKYSFQTHDRLCFVME
Template Known Secondary structure  TTTTT
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   150.........160.........170... ......180.... .....190.........200.........210........
 
   450.........460.........470.........480....... ..490.........500.........510.........520........
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Query Sequence  MAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEE. SNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKA
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Template Sequence  YANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEP. . . . . . . . .
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   229230.........240.........250.........260.........270.........280.........290.........
 
   529530.........540.........550.........560.........570.........580.........590.........600........
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Query Sequence  QTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLC
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Template Sequence  . . . . . . . . EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLSGL
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   314.....320.........330.........340.... .....350.........360..... ....370.........380...
 
   609610...... ...620.........630.....
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Query Sequence  WTYDVENR. . . . . PGFAAVELRLRNYYYDVVN
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Template Sequence  LKKDPKQRLGGGSEDAKEI. . . MQHRFFAGIV
Template Known Secondary structure  T
SSTTTSTT
STTT...TSGGGTT

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   384.....390.........400.. .......410..
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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