Job Description P43405 Confidence 100.00% Date Fri May 25 09:37:32 BST 2012 Rank 191 Aligned Residues 250 % Identity 20% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

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		371	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.						440	.	.	.	.	.
Predicted Secondary structure																																																																							.	.	.	.	.
Query SS confidence																																																																							.	.	.	.	.
Query Sequence		T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	.	.	.	.	E	A	E	S	W	M
Query Conservation																																																																							.	.	.	.	.
Alig confidence																						.	.	.	.														.	.	.																														.	.	.	.	.
Template Conservation																						.	.	.	.														.	.	.
Template Sequence		I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	.	.	.	.	Q	G	E	N	V	A	V	K	I	F	S	S	R	.	.	.	D	E	K	S	W	F	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L	G	F	I	A	S	D	M	T	S	R	H	S	S	T	Q	L	W
Template Known Secondary structure												T	T									.	.	.	.	T	T										G	G	.	.	.	G														S					T	T	B												T	T
Template Predicted Secondary structure																						.	.	.	.														.	.	.
Template SS confidence
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.					.	.	230	.	.	.	.	.	.	.	.	.	240				.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
		446	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490									.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.
Predicted Secondary structure																																															.	.	.	.	.	.	.	.
Query SS confidence																																															.	.	.	.	.	.	.	.
Query Sequence		L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	.	.	.	.	.	.	.	.	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K
Query Conservation																																															.	.	.	.	.	.	.	.
Alig confidence																				.																											.	.	.	.	.	.	.	.
Template Conservation																				.
Template Sequence		L	I	T	H	Y	H	E	M	G	S	L	Y	D	Y	L	Q	L	T	.	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V
Template Known Secondary structure								T	T		B									.		B																					S		B		S	T	T		B						S			S	G	G	G					T	T	S								T	T
Template Predicted Secondary structure																				.
Template SS confidence
		281	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.		.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
		518	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.		.	.	.	.	.	540	.	.	.	.	.	.	.	.							.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.
Predicted Secondary structure																			.															.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																			.															.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	.	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	.	.	.	.	.	.	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																			.															.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																			.															.	.	.	.	.	.																				.											.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																											.
Template Sequence		M	H	S	Q	S	T	N	Q	L	D	V	G	N	N	P	R	V	G	T	K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V	V	P	N	D
Template Known Secondary structure					T	T	T	T													G	G	G							T	T				T	T																						T	.	T	B		B	T	T	B							T	T	T	T	T	S		S	S
Template Predicted Secondary structure																																																											.
Template SS confidence
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.
					579	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.							.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.																			.	.	.	.	.	.
Query SS confidence		.	.	.																			.	.	.	.	.	.
Query Sequence		.	.	.	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	.	.	.	.	.	.	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y
Query Conservation		.	.	.																			.	.	.	.	.	.
Alig confidence		.	.	.																			.	.	.	.	.	.
Template Conservation
Template Sequence		P	S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T	L	T	K	I
Template Known Secondary structure												T	T	S								G	G	G	G	G	S																S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		439	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions