Job Description P43405 Confidence 100.00% Date Fri May 25 09:37:32 BST 2012 Rank 65 Aligned Residues 262 % Identity 37% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.			.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.
Predicted Secondary structure																																								.	.
Query SS confidence																																								.	.
Query Sequence		D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	.	.	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y
Query Conservation																																								.	.
Alig confidence														.	.	.	.	.	.	.	.																			.	.																	.
Template Conservation														.	.	.	.	.	.	.	.																																					.
Template Sequence		D	P	T	V	F	H	K	R	Y	L	K	K	.	.	.	.	.	.	.	.	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	.	A	G	P	Q	H	R	S	G	W	K	Q	E	I	D	I	L	R	T	L	Y	H	E	H
Template Known Secondary structure								G	G	G				.	.	.	.	.	.	.	.								S	S										T	T	S	S	S												S	S	.																						T	T
Template Predicted Secondary structure														.	.	.	.	.	.	.	.																																					.
Template SS confidence
		888	.	890	.	.	.	.	.	.	.	.	.									900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.		.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.
		432	.	.	.	.	.	.	.	440	.	.	.				.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.
Predicted Secondary structure														.	.	.
Query SS confidence														.	.	.
Query Sequence		I	V	R	M	I	G	I	C	E	A	E	S	.	.	.	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A
Query Conservation														.	.	.
Alig confidence														.	.	.																		.
Template Conservation																																		.
Template Sequence		I	I	K	Y	K	G	C	C	E	D	A	G	A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	.	P	R	H	S	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V
Template Known Secondary structure		B										T	T	T	T										T	T		B					G	.	G	G	S																								T	T				S			S	G	G	G						T	T
Template Predicted Secondary structure																																		.
Template SS confidence
		959	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990		.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.
		509	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.
Predicted Secondary structure																																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																	.	.	.	.																																									.							.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																	.	.	.	.																																									.
Template Sequence		K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	.	.	.	.	E	Y	R	V	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	A	Q
Template Known Secondary structure							T	T						T	T		.	.	.	.			B						G	G	G								S		B																			T	.	T	T		G	G	G	S											S	T	T
Template Predicted Secondary structure																	.	.	.	.																																									.
Template SS confidence
		1038	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.					.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.
			575	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y	Y
Query Conservation		.
Alig confidence		.
Template Conservation
Template Sequence		G	Q	M	T	V	L	R	L	T	E	L	L	E	R	G	E	R	L	P	R	P	D	K	C	P	A	E	V	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	E	N	L	I	P	I	L	K	T	V	H
Template Known Secondary structure		G	G	G											T	T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1117	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions