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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank40Aligned Residues262
% Identity35%Templatec3lxkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   365....370.........380.........390. ........400.........410.........420.........430.........440..
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Query Sequence  LDRKLLTLEDKELGSGNFGTVKKGYYQ. . MKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAE
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Template Sequence  IFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHS. . GPDQQRDFQREIQILKALHSDFIVKYRGVSYGP
Template Known Secondary structure  B

GGGTT
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T


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   816...820.........830.........840.........850.........860 .........870.........880.........890...
 
   443 ......450.........460 .........470.........480.........490.........500.........510........
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Query Sequence  S. . . WMLVMEMAELGPLNKYL. QQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKA
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Template Sequence  GRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKL
Template Known Secondary structure  SS


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   894.....900.........910.........920.........930.........940.........950.........960.........970...
 
   519520.........530.........540.........550.........560.........570..... ....580........
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Query Sequence  LRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRG. . . . . . . . . . MKGSEVTAMLEKG
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Template Sequence  LPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFT. YCDKSCSPSAEFLRMMVPALSRLLELLEEG
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   974.....980.........990.........1000.........1010.........1020.. .......1030.........1040.........1050..
 
   589590.........600.........610.........620.........
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Query Sequence  ERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY
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Template Sequence  QRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML
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   1058.1060.........1070.........1080.........1090........
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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