Job Description P43405 Confidence 100.00% Date Fri May 25 09:37:32 BST 2012 Rank 197 Aligned Residues 281 % Identity 17% Template c3h9rA_ PDB info PDB header:isomerase/protein kinase Chain: A: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the kinase domain of type i activin receptor2 (acvr1) in complex with fkbp12 and dorsomorphin Resolution 2.35 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		335	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	P	Q	R	E	A	L	P	M	D	T	E	V	Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K
Query Conservation
Alig confidence																																																										.	.	.	.														.	.	.
Template Conservation																																																										.	.	.	.														.	.	.
Template Sequence		T	T	N	V	G	D	S	T	L	A	D	L	L	D	H	S	C	T	S	G	S	G	S	G	L	P	F	L	V	Q	R	T	V	A	R	Q	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	.	.	.	.	Q	G	E	N	V	A	V	K	I	F	S	S	R	.	.	.	D	E	K	S
Template Known Secondary structure					T	T										T			S	T	T			S	S	S										T	T											T	T									.	.	.	.	T	T										G	G	.	.	.	G
Template Predicted Secondary structure																																																										.	.	.	.														.	.	.
Template SS confidence
		172	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.					.	.	230	.	.	.	.	.	.	.	.	.	240				.	.	.	.
		415	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.
Predicted Secondary structure																											.																																																.	.	.	.	.	.	.
Query SS confidence																											.																																																.	.	.	.	.	.	.
Query Sequence		D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	.	.	.	.	.	.	.
Query Conservation																											.																																																.	.	.	.	.	.	.
Alig confidence																											.																																																.	.	.	.	.	.	.
Template Conservation
Template Sequence		W	F	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L	G	F	I	A	S	D	M	T	S	S	T	Q	L	W	L	I	T	H	Y	H	E	M	G	S	L	Y	D	Y	L	Q	L	T	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H	I	E	I	F	G	T	Q
Template Known Secondary structure												S					T	T	B																						T	T		B										B																							B		S	T	T
Template Predicted Secondary structure
Template SS confidence
		245	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.
			487	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A
Query Conservation		.
Alig confidence		.																																														.	.	.	.	.	.
Template Conservation																																																.	.	.	.	.	.
Template Sequence		G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V	M	H	R	V	G	T	K	R	Y	M	A	P	E	V	.	.	.	.	.	.	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V
Template Known Secondary structure			B						S				G	G	G					T	T	S								T	T									G	G	G						.	.	.	.	.	.		T	T				T	T
Template Predicted Secondary structure																																																.	.	.	.	.	.
Template SS confidence
		328	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.							.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.
		566	.	.	.	570	.	.	.	.	.	.	.	.	.																580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.							.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.
Predicted Secondary structure																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Query SS confidence																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Query Sequence		F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	.	.	.	.	.	.	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L
Query Conservation																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Alig confidence				.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Template Conservation				.
Template Sequence		A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V	V	P	N	D	P	S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K
Template Known Secondary structure			T	.	T	B		B	T	T	B							T	T	T	T	T	S		S	S											T	T	S								G	G	G	G	G	S												T	T			S	S	G	G	G	S
Template Predicted Secondary structure				.
Template SS confidence
		415	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.
		625	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	L	R	N	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	L	T	K	I
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		494	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions