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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank82Aligned Residues262
% Identity34%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   354.....360.........370.........380.........390. ........400.........410.........420.........430.
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Query Sequence  DPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQ. . MKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPY
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Template Sequence  DPTQFEERHLKF. . . . . . . . LQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHS. . TEEHLRDFEREIEILKSLQHDN
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   840.........850. ........860.........870.........880....... ..890.........900.........
 
   432.......440.........450.........460 .........470.........480.........490.........500.........510
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Query Sequence  IVRMIGICEAESWMLVMEMAELGPLNKYL. QQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKI
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Template Sequence  IVKYKGVCY. SNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKI
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   910........ .920.........930.........940.........950.........960.........970.........980........
 
   511........520.........530.........540.........550.........560.........570.....
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Query Sequence  SDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRG. . . . . . . . . . . . . . .
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Template Sequence  GDFGLTKVLPQDKEKVKEPGESP. . IFWYAPESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQG
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   993......1000.........1010..... ....1020.........1030.........1040....... ..1050.........1060.........
 
   576...580.........590.........600.........610.........620.........
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Query Sequence  . MKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY
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Template Sequence  QMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI
Template Known Secondary structure  STT





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   1072.......1080.........1090.........1100.........1110.........1120......
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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