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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank203Aligned Residues236
% Identity23%Templatec3fmeA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6; PDBTitle: crystal structure of human mitogen-activated protein kinase kinase 62 (mek6) activated mutant (s207d, t211d)
Resolution2.26 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   369370.........380.........390.........400.........410.........420.........430......... 440.......
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Query Sequence  LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWMLV
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Template Sequence  DDLEPIMELGRGAYGVVEKMRHVPSG. . QIMAVKRIRNS. . . QEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWIC
Template Known Secondary structure  GG
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   51........60.........70...... ...80....... ..90.........100.........110.........120.....
 
   448.450.........460 .........470.........480...... ...490.........500.........510.........520...
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Query Sequence  MEMAELGPLNKYL. . . QQNRHVKDKNIIELVHQVSMGMKYLE. ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE
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Template Sequence  MELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFAGCKP. . . . .
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   129130.........140.........150.........160.........170.........180.........190.........200...
 
   524.....530.........540.... .....550.........560.........570....... ..580.........590.........
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Query Sequence  NYYKAQTHGKWPVKWYAPECI. . NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMK. . GSEVTAMLEKGERMGCPAGCPR
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Template Sequence  . . . . . . . . . . . . . . YMAPERINPELNQYSVKSDIWSLGITMIELAI. LRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSA
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   219220.........230.........240.........250 .........260.........270.........280...
 
   600.........610.........620.........630..
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Query Sequence  EMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD
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Template Sequence  EFVDFTSQCLKKNSKERPTYPEL. . . MQHPFFT
Template Known Secondary structure  T
SSGGGS

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   286...290.........300........ .310.....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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