Job Description P43405 Confidence 100.00% Date Fri May 25 09:37:32 BST 2012 Rank 52 Aligned Residues 259 % Identity 37% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.			.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.
Predicted Secondary structure																																								.	.
Query SS confidence																																								.	.
Query Sequence		D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	.	.	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y
Query Conservation																																								.	.
Alig confidence														.	.	.	.	.	.	.	.																			.	.																	.	.	.	.	.	.
Template Conservation														.	.	.	.	.	.	.	.																																					.	.	.	.	.	.
Template Sequence		D	P	T	H	F	E	K	R	F	L	K	R	.	.	.	.	.	.	.	.	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	P	H	.	.	.	.	.	.	I	A	D	L	K	K	E	I	E	I	L	R	N	L	Y	H	E	N
Template Known Secondary structure			T	T	S			G	G	G				.	.	.	.	.	.	.	.								S	S										T	T	S	S	S		S												.	.	.	.	.	.													T				T	T
Template Predicted Secondary structure														.	.	.	.	.	.	.	.																																					.	.	.	.	.	.
Template SS confidence
		866	.	.	.	870	.	.	.	.	.	.	.									.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.							.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.
		432	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460		.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510
Predicted Secondary structure																															.
Query SS confidence																															.
Query Sequence		I	V	R	M	I	G	I	C	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	.	Q	Q	N	R	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I
Query Conservation																															.
Alig confidence																															.
Template Conservation
Template Sequence		I	V	K	Y	K	G	I	C	T	E	N	G	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I
Template Known Secondary structure		B																				T	T		B					T	G	G	G	T	T	T																							T	T				S			S	G	G	G						T	T
Template Predicted Secondary structure
Template SS confidence
		937	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.
		511	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.																.	.
Predicted Secondary structure																																																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	G
Query Conservation																																																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																									.	.																																	.						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																									.	.																																	.
Template Sequence		G	D	F	G	L	T	K	A	I	E	T	D	K	E	T	V	K	D	D	R	D	S	P	.	.	V	F	W	Y	A	P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	.	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q
Template Known Secondary structure					T	T						T	T					S			T	T			.	.	G	G	G																													T	.	T	T		G	G	G												S			G	G
Template Predicted Secondary structure																									.	.																																	.
Template SS confidence
		1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.			.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.		.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.
		576	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	T	V	T	R	L	V	N	T	L	K	E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L
Template Known Secondary structure		G											T	T							T	T												T			S	S	G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		1099	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions