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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank152Aligned Residues253
% Identity24%Templatec3eqiA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 1; PDBTitle: x-ray structure of the human mitogen-activated protein kinase kinase 12 (mek1) in a binary complex with adp and mg2p
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   368.370.........380.........390.........400.........410.........420.........430......... 440......
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Query Sequence  KLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWML
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Template Sequence  DDDFEKISELGAGNGGVVFKVSHKPSG. . LVMARKLIHLEI. KPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISI
Template Known Secondary structure  GGG

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   65....70.........80.........90. ........100... ......110.........120.........130.........140.
 
   447..450.........460.........470.........480........ .490.........500.........510.........520.....
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Query Sequence  VMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEES. NFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENY
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Template Sequence  CMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN
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   142.......150.........160.........170.........180.........190.........200.........210.........220.
 
   526...530.........540.........550.........560.........570......... 580.........590..
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Query Sequence  YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGS. . . . . . . . . . . . . EVTAMLEKGERMG
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Template Sequence  SFVGTR. . . . . SYMSPERLQGTHYSVQSDIWSMGLSLVEMAV. GRYPIPPPDAKELELMFGCPMAIFELLDYIVNEPPPK
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   222..... ..230.........240.........250........ .260.........270.........280.........290.....
 
   593.. ....600.........610.........620.........630..
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Query Sequence  CPA. GCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD
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Template Sequence  LPSGVFSLEFQDFVNKCLIKNPAERADLKQL. . . MVHAFIK
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   325....330.........340.........350..... ....360..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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