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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank194Aligned Residues241
% Identity24%Templatec3db8A_
PDB info PDB header:transferaseChain: A: PDB Molecule:polo-like kinase 1; PDBTitle: crystal structure of an activated (thr->asp) polo-like2 kinase 1 (plk1) catalytic domain in complex with compound3 041
Resolution3.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   356...360.........370.........380.........390.........400........ .410.........420.........430....
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Query Sequence  EEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA. NDPALKDELLAEANVMQQLDNPYIVR
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Template Sequence  KEIPDVLVDPRTMKRYMRGRFLGKGGFAKCYEITDMDTK. . EVFAGKVVPKSMLLKPHQKEKMSTEIAIHKSLDNPHVVG
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   24.....30.........40.........50.........60.. .......70.........80.........90.........100.
 
   435.... 440.........450.........460.........470.........480.........490.........500.........510...
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Query Sequence  MIGIC. EAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDF
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Template Sequence  FHGFFEDDDFVYVVLEICRRRSLLELHKRRKAVTEPEARYFMRQTIQGVQYLHNNRVIHRDLKLGNLFLNDDMDVKIGDF
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   102.......110.........120.........130.........140.........150.........160.........170.........180.
 
   514.....520.........530.........540.........550.........560.........570.........580.........590...
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Query Sequence  GLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGC
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Template Sequence  GLATKI. . . . . . . . . . . . . . . . . . . . . . . . . . . . . HSFEVDIWSLGCILYTLLV. GKPPFETSCLKETYIRIKKNE. YSV
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   182..... ..190.........200...... ...210.........220....... ..230
 
   594.....600.........610.........620.........630..
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Query Sequence  PAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD
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Template Sequence  PRHINPVASALIRRMLHADPTLRPSVAEL. . . LTDEFFT
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   257..260.........270.........280..... ....290..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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