Job Description P43405 Confidence 100.00% Date Fri May 25 09:37:32 BST 2012 Rank 198 Aligned Residues 254 % Identity 33% Template c3c1xA_ PDB info PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor Resolution 2.17 Å

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		361	.	.	.	.	.	.	.	.	370	.	.	.		.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.		.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.
Predicted Secondary structure															.																						.
Query SS confidence															.																						.
Query Sequence		K	E	V	Y	L	D	R	K	L	L	T	L	E	.	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	.	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I
Query Conservation															.																						.
Alig confidence															.																						.																	.
Template Conservation																																																						.
Template Sequence		Q	H	V	V	I	G	P	S	S	L	I	V	H	F	N	E	V	I	G	R	G	H	F	G	C	V	Y	H	G	T	L	L	D	N	D	G	K	K	I	H	C	A	V	K	S	L	N	R	I	T	D	I	.	G	E	V	S	Q	F	L	T	E	G	I	I	M	K	D	F	S	H	P	N	V	L	S	L	L	G	I
Template Known Secondary structure		T	T	T	B			S	T	T													S	S	S										T	T	T												S		S		S	.											T	T	S	T	T				T	T	B
Template Predicted Secondary structure																																																						.
Template SS confidence
		1067	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.		.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.
		439			440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460		.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.
Predicted Secondary structure			.	.																						.
Query SS confidence			.	.																						.
Query Sequence		C	.	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	.	Q	Q	N	R	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L
Query Conservation			.	.																						.
Alig confidence			.	.																						.
Template Conservation
Template Sequence		C	L	R	S	E	G	S	P	L	V	V	L	P	Y	M	K	H	G	D	L	R	N	F	I	R	N	E	T	H	N	P	T	V	K	D	L	I	G	F	G	L	Q	V	A	K	G	M	K	F	L	A	S	K	K	F	V	H	R	D	L	A	A	R	N	C	M	L	D	E	K	F	T	V	K	V	A	D	F	L	P
Template Known Secondary structure						S	S										T	T		B								T	T				B																					T	T				S				G	G	G					T	T
Template Predicted Secondary structure
Template SS confidence
		1146	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.
		516	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A
Query Conservation
Alig confidence			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	W	M	A	L	E	S	L	Q	T	Q	K	F	T	T	K	S	D	V	W	S	F	G	V	L	L	W	E	L	M	T	R	G	A	P	P	Y	P	D	V	N	T	F	D	I	T	V	Y	L	L	Q	G	R	R	L	L	Q	P	E
Template Known Secondary structure		G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	S																												T	T	S			S		T	T	S		S	S								T	T							T
Template Predicted Secondary structure			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1247																					.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y	Y	Y	D	V	V	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	C	P	D	P	L	Y	E	V	M	L	K	C	W	H	P	K	A	E	M	R	P	S	F	S	E	L	V	S	R	I	S	A	I	F	S	T	F	I	G
Template Known Secondary structure		T													T		S	S	G	G	G	S																T			S
Template Predicted Secondary structure
Template SS confidence
		1307	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions