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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank260Aligned Residues228
% Identity24%Templatec3alnB_
PDB info PDB header:transferaseChain: B: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 4; PDBTitle: crystal structure of human non-phosphorylated mkk4 kinase domain2 complexed with amp-pnp
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   353......360.........370.........380.........390.........400.........410.........420.........430..
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Query Sequence  ADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYI
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Template Sequence  SGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSG. . QIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYI
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   84.....90.........100.........110.........120..... ....130.........140.........150.........160.
 
   433...... 440.........450.........460 .........470.........480........ .490.........500......
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Query Sequence  VRMIGIC. EAESWMLVMEMAELGPLNKYL. . . . QQNRHVKDKNIIELVHQVSMGMKYLEES. NFVHRDLAARNVLLVTQH
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Template Sequence  VQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSG
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   162.......170.........180.........190.........200.........210.........220.........230.........240.
 
   507..510.........520.........530.........540.........550.........560.........570.........580......
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Query Sequence  YAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLE
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Template Sequence  NIKLCDFGIS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . GQLYDVRSDVWSLGITLYELAT. GRFPYPDPP. . . . . . . . .
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   242.......250. ........260.........270... ......280..
 
   587..590.........600.........610.........620..
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Query Sequence  KGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV
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Template Sequence  . QLSNSEEREFSPSFINFVNLCLTKDESKRPKYKEL
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   327..330.........340.........350.........360.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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