Job Description P43405 Confidence 100.00% Date Fri May 25 09:37:32 BST 2012 Rank 181 Aligned Residues 261 % Identity 36% Template c2yhvA_ PDB info PDB header:transferase Chain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase Resolution 1.90 Å

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		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y
Query Conservation
Alig confidence																							.	.	.	.															.	.	.	.	.											.
Template Conservation																							.	.	.	.															.	.	.	.	.											.
Template Sequence		F	A	G	K	T	S	S	I	S	D	L	K	E	V	P	R	K	N	I	T	L	.	.	.	.	I	R	G	L	A	F	G	E	V	Y	E	G	Q	V	.	.	.	.	.	P	L	Q	V	A	V	K	T	L	P	.	E	V	C	S	E	Q	D	E	L	D	F	L	M	E	A	L	I	I	S	K	F	N	H	Q	N
Template Known Secondary structure			T	T					G	G	G	S		B			G	G	G				.	.	.	.							S								.	.	.	.	.											.	S	S																						T	T
Template Predicted Secondary structure																							.	.	.	.															.	.	.	.	.											.
Template SS confidence
		1098	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.					.	1120	.	.	.	.	.	.	.	.	.	1130	.	.						.	.	.	.	.	.	.	1140	.	.		.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.
		432	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.								.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.
Predicted Secondary structure										.																										.	.	.	.	.	.	.
Query SS confidence										.																										.	.	.	.	.	.	.
Query Sequence		I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	.	.	.	.	.	.	.	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V
Query Conservation										.																										.	.	.	.	.	.	.
Alig confidence										.																										.	.	.	.	.	.	.
Template Conservation
Template Sequence		I	V	R	C	I	G	V	S	L	Q	S	L	P	R	F	I	L	M	E	L	M	A	G	G	D	L	K	S	F	L	R	E	T	R	P	R	P	S	Q	P	S	S	L	A	M	L	D	L	L	H	V	A	R	D	I	A	C	G	C	Q	Y	L	E	E	N	H	F	I	H	R	D	I	A	A	R	N	C	L	L	T
Template Known Secondary structure		B									S	S	S	S									T	T										T				S	S	S	T	T	S																							T	T				S				G	G	G				S
Template Predicted Secondary structure
Template SS confidence
		1179	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.
		504	.	.	.				.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580
Predicted Secondary structure						.	.	.
Query SS confidence						.	.	.
Query Sequence		T	Q	H	Y	.	.	.	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E
Query Conservation						.	.	.
Alig confidence						.	.	.															.	.	.	.	.	.	.
Template Conservation																							.	.	.	.	.	.	.
Template Sequence		C	P	G	P	G	R	V	A	K	I	G	D	F	G	M	A	R	D	I	Y	R	.	.	.	.	.	.	.	G	G	C	A	M	L	P	V	K	W	M	P	P	E	A	F	M	E	G	I	F	T	S	K	T	D	T	W	S	F	G	V	L	L	W	E	I	F	S	L	G	Y	M	P	Y	P	S	K	S	N	Q	E
Template Known Secondary structure			S	S	T	T																	.	.	.	.	.	.	.			G	G	G	S		G	G	G																													T	T	S			S	S	T	T
Template Predicted Secondary structure																							.	.	.	.	.	.	.
Template SS confidence
		1259	1260	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.								1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.
		581	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	L	E	F	V	T	S	G	G	R	M	D	P	P	K	N	C	P	G	P	V	Y	R	I	M	T	Q	C	W	Q	H	Q	P	E	D	R	P	N	F	A	I	I	L	E	R	I	E	Y	C
Template Known Secondary structure								T	T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1338	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions