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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank261Aligned Residues259
% Identity25%Templatec2vagA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity protein kinase clk1; PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor
Resolution1.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   368.370.........380.........390.........400.........410.........420.........430.. .......440.
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Query Sequence  KLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYI. . . . . . VRMIGICEA
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Template Sequence  SARYEIVDTLGEGAFGKVVECIDH. KAGGRHVAVKIVK. . . NVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEH
Template Known Secondary structure  TTTTTT.TTTT
...SS
TT
TT
B

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   158.160.........170.........180. ........190.... .....200.........210.........220.........230...
 
   442.......450.........460 .........470.........480.........490.........500.........510.........
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Query Sequence  ESWMLVMEMAELGPLNKYL. . QQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKAL
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Template Sequence  HGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNKRDERTL
Template Known Secondary structure  TT



BTTT



TT




GGGS





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   234.....240.........250.........260.........270.........280.........290.........300.........310...
 
   520.. .......530.........540.........550.........560.........570.........580.......
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Query Sequence  RAD. . . . . . . . ENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK. . . .
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Template Sequence  INPDIKVVDFGSATYDDEHHSTLVRHYRAPEVILALGWSQPCDVWSIGCILIEYYL. GFTVFPTHDSKEHLAMMERILGP
Template Known Secondary structure  S





SS
TTS


S



S

TTS

ST.SS
S


S

S
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   317..320.........330.........340.........350.........360.........370.. .......380.........390.....
 
   588.590.........600.........610.........620........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRN
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Template Sequence  LPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREA. . . LKH
Template Known Secondary structure 


S
GGGTT


TTS


GGGG
S

ST
SSTTTS

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   398.400.........410.........420.........430.........440.........450.........460.........470. ...
 
   629630....
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Query Sequence  YYYDVV
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Template Conservation 
 
  
Template Sequence  PFFDLL
Template Known Secondary structure  GGGGGG
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   475....480
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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