|   |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | |
|
. | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | S | P | Y | A | D | P | E | E | I | R | P | K | E | V | Y | L | D | R | K | L | L | T | L | E | D | K | E | L | G | S | G | N | F | G | T | V | K | K | G | Y | Y | Q | . |
. |
M | K | K | V | V | K | T | V | A | V | K | I | L | K | N | E | A | N | D | P | A | L | K | D | E | L | L | A | E | A | N | V | M | Q | Q |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
| Template Sequence |   |
E | L | P | E | D | P | K | W | E | F | P | R | D | K | L | T | L | . |
. |
. |
. |
. |
. |
. |
. |
G | K | P | L | G | E | G | A | F | G | Q | V | V | M | A | E | A | V | G | I | D | K | D | K | P | V | T | V | A | V | K | M | L | K | D | D | . |
A | T | E | K | D | L | S | D | L | V | S | E | M | E | M | M | K | M |
| Template Known Secondary structure |   |
|
|
|
|
| T | T | T | B |
|
| G | G | G |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | T | T |
| S | T | T |
|
|
|  |  |  |  |  |  |
|
| T | T | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
467 | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | |
520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . |
|   |
|   |   |
427 | |
. | . | 430 | . | . | . | . | . | . | . | . | . | |
440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
| . |
|
|
|
|  |  |  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|  |
| Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | . |
D | N | P | Y | I | V | R | M | I | G | I | C | . |
E | A | E | S | W | M | L | V | M | E | M | A | E | L | G | P | L | N | K | Y | L | Q | Q | N | R | H | . |
. |
. |
. |
. |
. |
. |
V | K | D | K | N | I | I | E | L | V | H | Q | V | S | M | G | M | K | Y | L | E | E | S | N | F | V | H | R | D | L | A | A |
| Query Conservation |   |
| . |   |
|
|
|
|
|   |
|   |
|   |   | . |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |
| Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
I | G | K | H | K | N | I | I | N | L | L | G | A | C | T | Q | D | G | P | L | Y | V | I | V | E | Y | A | S | K | G | N | L | R | E | Y | L | R | A | R | R | P | P | G | M | E | S | Y | Q | M | T | F | K | D | L | V | S | C | T | Y | Q | L | A | R | G | M | E | Y | L | A | S | Q | K | C | I | H | R | D | L | A | A |
| Template Known Secondary structure |   |
 |
|
|
| T | T | B |
|
|  |  |  |  |  |
| S | S | S |
|
|  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  | T | T | S |
| T | T |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
541 | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 |
|   |
|   |   |
498 | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | N | V | L | L | V | T | Q | H | Y | A | K | I | S | D | F | G | L | S | K | A | L | R | A | D | E | N | Y | Y | K | A | Q | T | H | G | K | W | P | V | K | W | Y | A | P | E | C | I | N | Y | Y | K | F | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | A | F | S | Y | G | Q | K | P | Y | R | G | M | K |
| Query Conservation |   |
  |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
R | N | V | L | V | T | E | N | N | V | M | K | I | A | D | F | G | L | A | R | D | I | . |
. |
. |
N | N | I | D | K | K | T | T | N | G | R | L | P | V | K | W | M | A | P | E | A | L | F | D | R | V | Y | T | H | Q | S | D | V | W | S | F | G | V | L | M | W | E | I | F | T | L | G | G | S | P | Y | P | G | I | P |
| Template Known Secondary structure |   |
G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T |
|  |  |
| . | . | . | T | T | T |
|
|
|
| S |
|
|
|
|
| G | G | G |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| S | S | T | T |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | |
|
|
. | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . |
|   |
|   |   |
578 | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | S | E | V | T | A | M | L | E | K | G | E | R | M | G | C | P | A | G | C | P | R | E | M | Y | D | L | M | N | L | C | W | T | Y | D | V | E | N | R | P | G | F | A | A | V | E | L | R | L | R | N | Y | Y |
| Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |
|
|
| Template Sequence |   |
V | E | E | L | F | K | L | L | K | E | G | H | R | M | D | K | P | A | N | C | T | N | E | L | Y | M | M | M | R | D | C | W | H | A | V | P | S | Q | R | P | T | F | K | Q | L | V | E | D | L | D | R | I | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
709 | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . |
|   |