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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank1Aligned Residues533
% Identity60%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   7..10.........20.........30.........40.........50.........60.........70.........80......
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Query Sequence  ADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPA
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Template Conservation 
       
 

 


  

  
   
  

 



 
    
   

      
 
  
         
     
 

 
Template Sequence  PDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPA
Template Known Secondary structure 

TTSS
TTB
BS

TTT

TT
TTBTT
TT
TTS
TTS

BSS
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   2.......10.........20.........30.........40.........50.........60.........70.........80.
 
   87..90.........100.........110.........120.........130.........140.........150.........160......
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Query Sequence  DLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKM
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Template Conservation   

  
      
   
  

  
                                         
              
Template Sequence  ELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERM
Template Known Secondary structure  TS

TTSSS


SB



TT


B




TTS
TTTS
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   82.......90.........100.........110.........120.........130.........140.........150.........160.
 
   167..170.........180.........190.........200.........210.........220.........230.........240......
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Query Sequence  PWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSY
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Template Sequence  PWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLKL
Template Known Secondary structure  TTB
TT

SSS


TT

SSTTTT
TT


TTS
SS
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   162.......170.........180.........190.........200.........210.........220.........230.........240.
 
   247..250.........260.........270.........280.........290.........300.........310.........320......
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Query Sequence  KADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPE
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Template Conservation      
   
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Template Sequence  KADGLIYCLKEACPN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 

TT
SS


SB


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   242.......250......
 
   327..330.........340.........350.........360.........370.........380.........390.........400......
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Query Sequence  LAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKN
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Template Sequence  . . . . . . . . . . . . . . . . MDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQ
Template Known Secondary structure  ................



S
SSSSS
S
SS



SB

TTS
SSS
SS



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   310.........320.........330.........340.........350.........360.........370...
 
   407..410.........420.........430.........440.........450.........460 .........470.........480.....
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Query Sequence  EANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYL. QQNRHVKDKNIIELVHQVSMGMKYL
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Template Conservation      .        
  

  
 

 

   
        

 
    


   
                 

   
  
Template Sequence  GTEK. ADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYL
Template Known Secondary structure 

SS.TTTT


TTB

SSS

TT
BTT
TTTS
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   374... ..380.........390.........400.........410.........420.........430.........440.........450..
 
   486...490.........500.........510.........520.........530.........540.........550.........560.....
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Query Sequence  EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEA
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Template Sequence  EEKNFVHRNLAARNVLLVNRHYAKISDFGLSKAL. . . . . . . . . . . . . . GPLKWYAPECINFRKFSSRSDVWSYGVTMWEA
Template Known Secondary structure  TT


S

SGGGTT


STTTT
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TTS




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   453......460.........470.........480...... ...490.........500.........510........
 
   566...570.........580.........590.........600.........610.........620.........630.....
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Query Sequence  FSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
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Template Conservation   
 
  
            
        
   
     

  
    
  

    
   
         
Template Sequence  LSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLAS
Template Known Secondary structure  TTS

TTTT

STT





TT

TT
SSTTTS

S
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   533......540.........550.........560.........570.........580.........590.........600..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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