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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank250Aligned Residues253
% Identity23%Templatec2ojiA_
PDB info PDB header:transferaseChain: A: PDB Molecule:mitogen-activated protein kinase 1; PDBTitle: crystal structure of erk2 in complex with n-benzyl-4-(4-(3-2 chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   371........380.........390.........400.........410.........420.........430.........440.. ..
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Query Sequence  TLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAE. . . . . . SW
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Template Sequence  YTNLSYIGEGAYGMVCSAYDNVNK. . VRVAIKKISPFE. HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDV
Template Known Secondary structure  TTTTTT..

TT.S


TTB





SSTTT


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   23......30.........40...... ...50........ .60.........70.........80.........90.........
 
   445....450.........460.........470.........480.........490.........500.........510.........520....
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Query Sequence  MLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN
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Template Sequence  YIVQDLMETDLYKLLKTQH. . LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHD
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S

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GGG
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   100.........110........ .120.........130.........140.........150.........160.........170.......
 
   525....530......... 540.........550.........560.........570.........580.........590....
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Query Sequence  YYKAQTHGKWPVKWY. APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCP. . . . . . . . .
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Template Sequence  HTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS. NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINL
Template Known Secondary structure  B

TT



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   178.180.........190.........200.........210.........220. ........230.........240.........250......
 
   595....600.........610.........620.........630..
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . AGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD
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Template Sequence  KARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQA. . . LAHPYLE
Template Known Secondary structure  TS







TTS
T
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   257..260.........270.........280.........290.........300..... ....310..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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