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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank73Aligned Residues261
% Identity23%Templatec2j51A_
PDB info PDB header:transferaseChain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
Resolution2.1 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   364.....370.........380.........390.........400.........410.........420.........430......... 440..
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Query Sequence  YLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAE
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Template Sequence  DLNPEDFWEIIGELGDGAFGKVYKAQNKETS. . VLAAAKVIDTK. . SEEELEDYMVEIDILASCDHPNIVKLLDAFYYEN
Template Known Secondary structure  SS
GGGTTTTTT
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S..SSTT


TTB

TT
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   27..30.........40.........50....... ..60........ .70.........80.........90.........100..
 
   443......450.........460 .........470.........480.........490.........500.........510.........520.
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Query Sequence  SWMLVMEMAELGPLNKYL. QQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRA
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Template Sequence  NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTR
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TTTS


TT



SGGG
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   103......110.........120.........130.........140.........150.........160.........170.........180..
 
   522.......530.........540.... .....550.........560.........570.........580......... 590....
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Query Sequence  DENYYKAQTHGKWPVKWYAPECI. . . . . NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGE. . RMGCP
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Template Sequence  TIQRRDSFIGTPY. . . WMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE. IEPPHHELNPMRVLLKIAKSEPPTLAQP
Template Known Secondary structure  S


S

T...T

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STTTSSTTT.SS
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   183......190..... ....200.........210.........220.........230 .........240.........250........
 
   595....600.........610.........620.........630.....
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Query Sequence  AGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
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Template Sequence  SRWSSNFKDFLKKCLEKNVDARWTTSQL. . . LQHPFVTVDS
Template Known Secondary structure  GGS
S
SSTTTS

...TTSGGG



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   259260.........270.........280...... ...290......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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