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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank20Aligned Residues268
% Identity39%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   359360.........370.........380.........390 .........400.........410.........420.........430.....
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Query Sequence  RPKEVYLDRKLLTLEDKELGSGNFGTVKKGYY. . . QMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM
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Template Sequence  EDPKWEFPRKNLVL. GKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLK. ENASPSELRDLLSEFNVLKQVNHPHVIKL
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TTTB

GGG.
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   713......720...... ...730.........740.........750.........760. ........770.........780.........790
 
   436... 440.........450.........460..... ....470.........480.........490.........500......
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Query Sequence  IGIC. EAESWMLVMEMAELGPLNKYLQQNRH. . . . . . . . VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQH
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Template Sequence  YGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGR
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   791........800.........810.........820.........830.........840.........850.........860.........870
 
   507..510.........520.........530.........540.........550.........560.........570.........580......
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Query Sequence  YAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLE
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Template Sequence  KMKISDFGLSRDV. YEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK
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TT

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   887..890......... 900.........910.........920.........930.........940.........950.........960.....
 
   587..590.........600.........610.........620.........
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Query Sequence  KGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY
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Template Sequence  TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM
Template Known Secondary structure  TT





TT

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   966...970.........980.........990.........1000........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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