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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank7Aligned Residues355
% Identity41%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   164.....170.........180.........190....... ..200........ .210.........220.........230.......
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Query Sequence  EKMPWFHGKISREESEQIVLIGSKTNGKFLIRAR. DNNGSYALCLL. . . . . HEGKVLHYRIDKDKTGKLSIPEGKKFDTL
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Template Sequence  ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTL
Template Known Secondary structure  GGSTTTT

TSTT

TT

SSSTT
TTTB

STT
SSTTSSS
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   119120.........130.........140.........150.........160.........170.........180.........190........
 
   238.240.........250.........260.........270.........280.........290.........300.........310.......
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Query Sequence  WQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQEST
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Template Sequence  QELVDHYKKGNDGLCQKLSVPCMSSKP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTSS
SS
SS


SB





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   199200.........210.........220.....
 
   318.320.........330.........340.........350.........360.........370.........380.........390.......
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Query Sequence  VSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVK
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QKPWEKDAWEIPRESLKL. EKKLGAGQFGEVWMATYN. . . KHT
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TT
SB

GGG.TTT...TT
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   226...230.........240... ......250.........260. ...
 
   398.400.........410.........420.........430.........440.........450.........460..... ....470.....
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Query Sequence  TVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRH. . VKDKNIIELV
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Template Sequence  KVAVKTMKPGSMS. . . VEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFS
Template Known Secondary structure 


SS
...T


TTB


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TT
BSTTGGG

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   265....270....... ..280.........290.........300.........310.........320.........330.........340.
 
   476...480.........490.........500.........510.........520.........530.........540.........550.....
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Query Sequence  HQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDV
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Template Sequence  AQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLAR. . . . . . . . . . . . . . . VIPIKWTAPEAINFGSFTIKSDV
Template Known Secondary structure  TT


S

SGGG
TT



TTGGG...............T

GGGS




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   342.......350.........360.........370.........380... ......390.........400......
 
   556...560.........570.........580.........590.........600.........610.........620.........630
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Query Sequence  WSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY
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Template Sequence  WSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFY
Template Known Secondary structure  TTT

SSTT

TT





TT

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SSGGGS

TTT
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   420.........430.........440.........450.........460.........470.........480.........490....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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