Job Description P43405 Confidence 100.00% Date Fri May 25 09:37:32 BST 2012 Rank 68 Aligned Residues 265 % Identity 34% Template c1yvjA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: crystal structure of the jak3 kinase domain in complex with2 a staurosporine analogue Resolution 2.55 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.			.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.
Predicted Secondary structure																																							.	.
Query SS confidence																																							.	.
Query Sequence		P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	.	.	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I
Query Conservation																																							.	.
Alig confidence													.	.	.	.	.	.	.	.																			.	.														.	.
Template Conservation													.	.	.	.	.	.	.	.																																		.	.
Template Sequence		P	T	I	F	E	E	R	H	L	K	Y	.	.	.	.	.	.	.	.	I	S	Q	L	G	K	G	N	F	G	S	V	E	L	C	R	Y	D	P	L	G	D	N	T	G	A	L	V	A	V	K	Q	L	.	.	Q	H	S	G	P	D	Q	Q	R	D	F	Q	R	E	I	Q	I	L	K	A	L	H	S	D	F	I
Template Known Secondary structure				B			G	G	G				.	.	.	.	.	.	.	.								S	S										S	S	S	S	S		S									.	.	S			S	T	T																		T	T	B
Template Predicted Secondary structure													.	.	.	.	.	.	.	.																																		.	.
Template SS confidence
		814	.	.	.	.	.	820	.	.	.	.									.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.			.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.
		433	.	.	.	.	.	.	440	.	.	.				.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.		.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.
Predicted Secondary structure													.	.	.																					.
Query SS confidence													.	.	.																					.
Query Sequence		V	R	M	I	G	I	C	E	A	E	S	.	.	.	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	.	R	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A
Query Conservation													.	.	.																					.
Alig confidence													.	.	.																					.
Template Conservation
Template Sequence		V	K	Y	R	G	V	S	Y	G	P	G	R	P	E	L	R	L	V	M	E	Y	L	P	S	G	C	L	R	D	F	L	Q	R	H	R	A	R	L	D	A	S	R	L	L	L	Y	S	S	Q	I	C	K	G	M	E	Y	L	G	S	R	R	C	V	H	R	D	L	A	A	R	N	I	L	V	E	S	E	A	H	V
Template Known Secondary structure											S	S	S	S										T	T		B								T	T	T	T																							T	T				S				G	G	G						T	T
Template Predicted Secondary structure
Template SS confidence
		884	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.
		509	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.
Predicted Secondary structure																																																																						.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																						.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																																						.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.																																																.									.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation												.	.																																																.
Template Sequence		K	I	A	D	F	G	L	A	K	L	.	.	L	P	L	D	K	D	V	V	R	E	P	G	Q	S	P	I	F	W	Y	A	P	E	S	L	S	D	N	I	F	S	R	Q	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	C	D	K	S	C	S	P	S	A	E	F	L	R	M	M	G	C	E	R
Template Known Secondary structure							S	S				.	.			T	T					S	S			S	S		G	G	G	S																													.	T	T		S	T	T	S												S	S
Template Predicted Secondary structure												.	.																																																.
Template SS confidence
		964	.	.	.	.	.	970	.	.	.			.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020		.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040
					577	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.
Predicted Secondary structure		.	.	.
Query SS confidence		.	.	.
Query Sequence		.	.	.	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y	Y	Y	D
Query Conservation		.	.	.
Alig confidence		.	.	.
Template Conservation
Template Sequence		D	V	P	A	L	C	R	L	L	E	L	L	E	E	G	Q	R	L	P	A	P	P	A	C	P	A	E	V	H	E	L	M	K	L	C	W	A	P	S	P	Q	D	R	P	S	F	S	A	L	G	P	Q	L	D	M	L	W	S	G
Template Known Secondary structure		S													T	T							T	T													T		S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		1043	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions