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Job DescriptionP43405
Confidence100.00%DateFri May 25 09:37:32 BST 2012
Rank3Aligned Residues373
% Identity40%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   164.....170.........180.........190....... ..200.........210.........220.........230.........240..
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Query Sequence  EKMPWFHGKISREESEQIVLIGSKTNGKFLIRAR. DNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVE
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Template Sequence  EKHSWYHGPVSRNAAEYLLSS. . GINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVH
Template Known Secondary structure  GGSTT

GGG..

TT
SSSTT
TT

TTS
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   142.......150.........160.. .......170.........180.........190.........200.........210.........
 
   243......250.........260.........270.........280.........290.........300.........310.........320..
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Query Sequence  HYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNP
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Template Sequence  HHSTVADGLITTLHYPAPK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT

TTSSS





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   220.........230........
 
   323......330.........340.........350.........360.........370.........380.........390.........400..
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Query Sequence  YEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVK
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Template Sequence  . . . . . . . . . . . . . . . . . . RNKPTVYGVSPNYDKWEMERTDITM. . . . . . . . KHKLGGGQYGEVYEGVWKKYS. . LTVAVK
Template Known Secondary structure  ..................
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SSS
SSSS

B

GGG........SGGGTTSSGGGT..
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   239240.........250.........260... ......270.........280.... .....290
 
   403......410.........420.........430......... 440.........450.........460.... .....470.........
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Query Sequence  ILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWMLVMEMAELGPLNKYLQQNR. . HVKDKNIIELVHQVS
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Template Sequence  TLKEDTME. . . VEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQIS
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TTB


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   291....... .300.........310.........320.........330.........340.........350.........360.......
 
   480.........490.........500.........510.........520.........530.........540.........550.........
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Query Sequence  MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFG
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Template Sequence  SAMEYLEKKNFIHRNLAARNCLVGENHLVKVADFGLSRLM. . TGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFG
Template Known Secondary structure  TT
S

SGGG
GGG


TT


..TT



TT



GGG



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   368.370.........380.........390.........400....... ..410.........420.........430.........440.....
 
   560.........570.........580.........590.........600.........610.........620.........630..
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Query Sequence  VLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD
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Template Sequence  VLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE
Template Known Secondary structure  TTS

SSTT

TTTTT





TT

T
SSGGGS

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   446...450.........460.........470.........480.........490.........500.........510........
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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