Phyre 2 Results for P43405

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Email | l.a.kelley@imperial.ac.uk
Description | P43405
Date | Fri May 25 09:37:32 BST 2012
Unique Job ID | 2db15a2455b16f33

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c2ozoA_
Top template information
PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Confidence and coverage
Confidence: | 100.0% | Coverage: | 84%
533 residues ( 84% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | A | S | S | G | M | A | D | S | A | N | H | L | P | F | F | F | G | N | I | T | R | E | E | A | E | D | Y | L | V | Q | G | G | M | S | D | G | L | Y | L | L | R | Q | S | R | N | Y | L | G | G | F | A | L | S | V | A | H | G | R | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | A | H | H | Y | T | I | E | R | E | L | N | G | T | Y | A | I | A | G | G | R | T | H | A | S | P | A | D | L | C | H | Y | H | S | Q | E | S | D | G | L | V | C | L | L | K | K | P | F | N | R | P | Q | G | V | Q | P | K | T | G | P | F
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | E | D | L | K | E | N | L | I | R | E | Y | V | K | Q | T | W | N | L | Q | G | Q | A | L | E | Q | A | I | I | S | Q | K | P | Q | L | E | K | L | I | A | T | T | A | H | E | K | M | P | W | F | H | G | K | I | S | R | E | E | S | E | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | I | V | L | I | G | S | K | T | N | G | K | F | L | I | R | A | R | D | N | N | G | S | Y | A | L | C | L | L | H | E | G | K | V | L | H | Y | R | I | D | K | D | K | T | G | K | L | S | I | P | E | G | K | K | F | D | T | L | W | Q | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | V | E | H | Y | S | Y | K | A | D | G | L | L | R | V | L | T | V | P | C | Q | K | I | G | T | Q | G | N | V | N | F | G | G | R | P | Q | L | P | G | S | H | P | A | T | W | S | A | G | G | I | I | S | R | I | K | S | Y | S | F | P | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | P | G | H | R | K | S | S | P | A | Q | G | N | R | Q | E | S | T | V | S | F | N | P | Y | E | P | E | L | A | P | W | A | A | D | K | G | P | Q | R | E | A | L | P | M | D | T | E | V | Y | E | S | P | Y | A | D | P | E | E | I | R | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  | ? | ? | ? |  |  |  |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | K | E | V | Y | L | D | R | K | L | L | T | L | E | D | K | E | L | G | S | G | N | F | G | T | V | K | K | G | Y | Y | Q | M | K | K | V | V | K | T | V | A | V | K | I | L | K | N | E | A | N | D | P | A | L | K | D | E | L | L | A | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | A | N | V | M | Q | Q | L | D | N | P | Y | I | V | R | M | I | G | I | C | E | A | E | S | W | M | L | V | M | E | M | A | E | L | G | P | L | N | K | Y | L | Q | Q | N | R | H | V | K | D | K | N | I | I | E | L | V | H | Q | V | S | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | G | M | K | Y | L | E | E | S | N | F | V | H | R | D | L | A | A | R | N | V | L | L | V | T | Q | H | Y | A | K | I | S | D | F | G | L | S | K | A | L | R | A | D | E | N | Y | Y | K | A | Q | T | H | G | K | W | P | V | K | W | Y | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | P | E | C | I | N | Y | Y | K | F | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | A | F | S | Y | G | Q | K | P | Y | R | G | M | K | G | S | E | V | T | A | M | L | E | K | G | E | R | M | G | C | P | A | G | C | P | R | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? |  |  |  | ? |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | .
Sequence |  | M | Y | D | L | M | N | L | C | W | T | Y | D | V | E | N | R | P | G | F | A | A | V | E | L | R | L | R | N | Y | Y | Y | D | V | V | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c2ozoA_ |

### PDB 2ozo chain A

Region: 7 - 635
Aligned: 533
Modelled: 534
Confidence: 100.0%
Identity: 60%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2
2 |
| c2fo0A_ |

### PDB 2fo0 chain A

Region: 164 - 632
Aligned: 373
Modelled: 380
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2
3 |
| c1oplA_ |

### PDB 1opl chain A

Region: 164 - 632
Aligned: 373
Modelled: 382
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2
4 |
| c1y57A_ |

### PDB 1y57 chain A

Region: 164 - 633
Aligned: 372
Modelled: 388
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2
5 |
| c2h8hA_ |

### PDB 2h8h chain A

Region: 164 - 633
Aligned: 372
Modelled: 385
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2
6 |
| c1k9aB_ |

### PDB 1k9a chain B

Region: 164 - 630
Aligned: 356
Modelled: 376
Confidence: 100.0%
Identity: 46%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2
7 |
| c2c0iA_ |

### PDB 2c0i chain A

Region: 164 - 630
Aligned: 355
Modelled: 362
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2
8 |
| c3cblA_ |

### PDB 3cbl chain A

Region: 164 - 629
Aligned: 340
Modelled: 358
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide

Phyre2
9 |
| c2j0kB_ |

### PDB 2j0k chain B

Region: 319 - 632
Aligned: 289
Modelled: 298
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.

Phyre2
10 |
| c2oq1A_ |

### PDB 2oq1 chain A

Region: 8 - 261
Aligned: 254
Modelled: 254
Confidence: 100.0%
Identity: 56%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2
11 |
| d1u59a_ |

### PDB 1u59 chain A

Region: 361 - 635
Aligned: 271
Modelled: 275
Confidence: 100.0%
Identity: 61%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
12 |
| c3zzwA_ |

### PDB 3zzw chain A

Region: 364 - 629
Aligned: 263
Modelled: 266
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2

Phyre2
13 |
| c3pfqA_ |

### PDB 3pfq chain A

Region: 260 - 635
Aligned: 368
Modelled: 376
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii

Phyre2
14 |
| d1qcfa3 |

### PDB 1qcf chain A domain 3

Region: 353 - 635
Aligned: 274
Modelled: 283
Confidence: 100.0%
Identity: 35%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
15 |
| c2acxB_ |

### PDB 2acx chain B

Region: 371 - 635
Aligned: 255
Modelled: 265
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp

Phyre2
16 |
| c3qa8A_ |

### PDB 3qa8 chain A

Region: 375 - 618
Aligned: 236
Modelled: 240
Confidence: 100.0%
Identity: 27%
PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2
17 |
| d1opja_ |

### PDB 1opj chain A

Region: 354 - 630
Aligned: 269
Modelled: 277
Confidence: 100.0%
Identity: 39%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
18 |
| d1xbba_ |

### PDB 1xbb chain A

Region: 363 - 635
Aligned: 264
Modelled: 273
Confidence: 100.0%
Identity: 99%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
19 |
| c1ym7C_ |

### PDB 1ym7 chain C

Region: 371 - 635
Aligned: 256
Modelled: 265
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)

Phyre2
20 |
| c2ivsA_ |

### PDB 2ivs chain A

Region: 359 - 629
Aligned: 268
Modelled: 271
Confidence: 100.0%
Identity: 39%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2ozoA_ |
|  | 100.0 | 60 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
2 | c2fo0A_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
3 | c1oplA_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
4 | c1y57A_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
5 | c2h8hA_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
6 | c1k9aB_ |
|  | 100.0 | 46 | PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
7 | c2c0iA_ |
|  | 100.0 | 41 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
8 | c3cblA_ |
|  | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
9 | c2j0kB_ |
|  | 100.0 | 37 | PDB header:transferase Chain: B: PDB Molecule:focal adhesion kinase 1; PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.
10 | c2oq1A_ |
|  | 100.0 | 56 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
11 | d1u59a_ |
|  | 100.0 | 61 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
12 | c3zzwA_ |
|  | 100.0 | 35 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2; PDBTitle: crystal structure of the kinase domain of ror2
13 | c3pfqA_ |
|  | 100.0 | 19 | PDB header:transferase Chain: A: PDB Molecule:protein kinase c beta type; PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
14 | d1qcfa3 |
|  | 100.0 | 35 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
15 | c2acxB_ |
|  | 100.0 | 21 | PDB header:transferase Chain: B: PDB Molecule:g protein-coupled receptor kinase 6; PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp
16 | c3qa8A_ |
|  | 100.0 | 27 | PDB header:immune system, signaling protein Chain: A: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta
17 | d1opja_ |
|  | 100.0 | 39 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
18 | d1xbba_ |
|  | 100.0 | 99 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
19 | c1ym7C_ |
|  | 100.0 | 21 | PDB header:transferase Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1; PDBTitle: g protein-coupled receptor kinase 2 (grk2)
20 | c2ivsA_ |
|  | 100.0 | 39 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
21 | c3c4yA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:rhodopsin kinase; PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
22 | c3ckxA_ |
| not modelled | 100.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 24; PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine
23 | d1qpca_ |
| not modelled | 100.0 | 40 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
24 | c3g0eA_ |
| not modelled | 100.0 | 34 | PDB header:transferase Chain: A: PDB Molecule:mast/stem cell growth factor receptor; PDBTitle: kit kinase domain in complex with sunitinib
25 | c3dpkA_ |
| not modelled | 100.0 | 35 | PDB header:transferase Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor; PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor
26 | d1lufa_ |
| not modelled | 100.0 | 36 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
27 | c1lufA_ |
| not modelled | 100.0 | 36 | PDB header:transferase Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk; PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation
28 | c1koaA_ |
| not modelled | 100.0 | 22 | PDB header:kinase Chain: A: PDB Molecule:twitchin; PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains
29 | c3soaA_ |
| not modelled | 100.0 | 20 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit PDBTitle: full-length human camkii
30 | c3q5iA_ |
| not modelled | 100.0 | 27 | PDB header:transferase Chain: A: PDB Molecule:protein kinase; PDBTitle: crystal structure of pbanka_031420
31 | d2j4za1 |
| not modelled | 100.0 | 24 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
32 | c2vwiC_ |
| not modelled | 100.0 | 29 | PDB header:transferase Chain: C: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structure of the osr1 kinase, a hypertension drug target
33 | c3plsA_ |
| not modelled | 100.0 | 33 | PDB header:transferase Chain: A: PDB Molecule:macrophage-stimulating protein receptor; PDBTitle: ron in complex with ligand amp-pnp
34 | d1k2pa_ |
| not modelled | 100.0 | 38 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
35 | c2c30A_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6; PDBTitle: crystal structure of the human p21-activated kinase 6
36 | c2pvfA_ |
| not modelled | 100.0 | 38 | PDB header:transferase Chain: A: PDB Molecule:fibroblast growth factor receptor 2; PDBTitle: crystal structure of tyrosine phosphorylated activated fgf receptor 22 (fgfr2) kinase domain in complex with atp analog and substrate3 peptide
37 | c2wtkC_ |
| not modelled | 100.0 | 23 | PDB header:transferase/metal-binding protein Chain: C: PDB Molecule:serine/threonine-protein kinase 11; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
38 | c2psqA_ |
| not modelled | 100.0 | 38 | PDB header:transferase Chain: A: PDB Molecule:fibroblast growth factor receptor 2; PDBTitle: crystal structure of unphosphorylated unactivated wild type2 fgf receptor 2 (fgfr2) kinase domain
39 | d2psqa1 |
| not modelled | 100.0 | 38 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
40 | c3lxkA_ |
| not modelled | 100.0 | 35 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
41 | d3bu3a1 |
| not modelled | 100.0 | 35 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
42 | d1t46a_ |
| not modelled | 100.0 | 34 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
43 | c1a81E_ |
| not modelled | 100.0 | 100 | PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
44 | c3fbvL_ |
| not modelled | 100.0 | 27 | PDB header:transferase, hydrolase Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1
45 | d1fmka3 |
| not modelled | 100.0 | 37 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
46 | d1yhwa1 |
| not modelled | 100.0 | 23 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
47 | d1p4oa_ |
| not modelled | 100.0 | 31 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
48 | c4eutA_ |
| not modelled | 100.0 | 24 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1; PDBTitle: structure of bx-795 complexed with unphosphorylated human tbk1 kinase-2 uld domain
49 | c3lijA_ |
| not modelled | 100.0 | 28 | PDB header:transferase Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp
50 | d1mp8a_ |
| not modelled | 100.0 | 39 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
51 | c2bujA_ |
| not modelled | 100.0 | 20 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 16; PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine
52 | c3eygA_ |
| not modelled | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
53 | c2a1aB_ |
| not modelled | 100.0 | 23 | PDB header:protein synthesis/transferase Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein PDBTitle: pkr kinase domain-eif2alpha complex
54 | d1uwha_ |
| not modelled | 100.0 | 28 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
55 | c2bmcD_ |
| not modelled | 100.0 | 25 | PDB header:transferase Chain: D: PDB Molecule:serine threonine-protein kinase 6; PDBTitle: aurora-2 t287d t288d complexed with pha-680632
56 | c2y7jB_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain, PDBTitle: structure of human phosphorylase kinase, gamma 2
57 | c3l9pA_ |
| not modelled | 100.0 | 35 | PDB header:transferase Chain: A: PDB Molecule:anaplastic lymphoma kinase; PDBTitle: crystal structure of the anaplastic lymphoma kinase catalytic domain
58 | c3cc6A_ |
| not modelled | 100.0 | 38 | PDB header:transferase Chain: A: PDB Molecule:protein tyrosine kinase 2 beta; PDBTitle: crystal structure of kinase domain of protein tyrosine kinase 2 beta2 (ptk2b)
59 | d1phka_ |
| not modelled | 100.0 | 23 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
60 | c3lvpD_ |
| not modelled | 100.0 | 34 | PDB header:transferase Chain: D: PDB Molecule:insulin-like growth factor 1 receptor; PDBTitle: crystal structure of bisphosphorylated igf1-r kinase domain (2p) in2 complex with a bis-azaindole inhibitor
61 | d1fgka_ |
| not modelled | 100.0 | 35 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
62 | c3dfaA_ |
| not modelled | 100.0 | 24 | PDB header:transferase Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920; PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum
63 | c3d9vA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:rho-associated protein kinase 1; PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil
64 | c2clqA_ |
| not modelled | 100.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5
65 | c3lxnA_ |
| not modelled | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
66 | c2qg5D_ |
| not modelled | 100.0 | 21 | PDB header:transferase Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase; PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840
67 | d2jfla1 |
| not modelled | 100.0 | 21 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
68 | c1yvjA_ |
| not modelled | 100.0 | 34 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: crystal structure of the jak3 kinase domain in complex with2 a staurosporine analogue
69 | d1mqba_ |
| not modelled | 100.0 | 37 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
70 | d1jksa_ |
| not modelled | 100.0 | 22 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
71 | d1jpaa_ |
| not modelled | 100.0 | 36 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
72 | c3hztA_ |
| not modelled | 100.0 | 29 | PDB header:transferase Chain: A: PDB Molecule:calcium-dependent protein kinase 3; PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860
73 | c2j51A_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
74 | c3d4qA_ |
| not modelled | 100.0 | 28 | PDB header:transferase Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
75 | d1sm2a_ |
| not modelled | 100.0 | 40 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
76 | c3p23B_ |
| not modelled | 100.0 | 25 | PDB header:hydrolase, transferase Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp
77 | c1mruB_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb; PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb.
78 | d1ckia_ |
| not modelled | 100.0 | 20 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
79 | c2pziA_ |
| not modelled | 100.0 | 18 | PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
80 | c2w1iB_ |
| not modelled | 100.0 | 34 | PDB header:transferase Chain: B: PDB Molecule:jak2; PDBTitle: structure determination of aurora kinase in complex with2 inhibitor
81 | c2qobA_ |
| not modelled | 100.0 | 35 | PDB header:transferase Chain: A: PDB Molecule:ephrin receptor; PDBTitle: human epha3 kinase domain, base structure
82 | c3fupB_ |
| not modelled | 100.0 | 34 | PDB header:transferase Chain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
83 | d1fvra_ |
| not modelled | 100.0 | 35 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
84 | c2cgvA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase chk1; PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening
85 | d1xjda_ |
| not modelled | 100.0 | 25 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
86 | c1xjdA_ |
| not modelled | 100.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:protein kinase c, theta type; PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution
87 | d1o6ya_ |
| not modelled | 100.0 | 23 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
88 | c2a27B_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: B: PDB Molecule:death-associated protein kinase 2; PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit
89 | c3v5qB_ |
| not modelled | 100.0 | 33 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
90 | d1nvra_ |
| not modelled | 100.0 | 22 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
91 | c2wtkB_ |
| not modelled | 100.0 | 18 | PDB header:transferase/metal-binding protein Chain: B: PDB Molecule:ste20-related kinase adapter protein alpha; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
92 | c2zv2A_ |
| not modelled | 100.0 | 21 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase kinase 2; PDBTitle: crystal structure of human calcium/calmodulin-dependent protein kinase2 kinase 2, beta, camkk2 kinase domain in complex with sto-609
93 | c3sxrA_ |
| not modelled | 100.0 | 37 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib
94 | c2wqmA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase nek7; PDBTitle: structure of apo human nek7
95 | c2bdwB_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: B: PDB Molecule:hypothetical protein k11e8.1d; PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii
96 | c2vz6A_ |
| not modelled | 100.0 | 20 | PDB header:transferase Chain: A: PDB Molecule:calcium calmodulin dependent protein kinase type ii alpha PDBTitle: structure of human calcium calmodulin dependent protein2 kinase type ii alpha (camk2a) in complex with indirubin3 e804
97 | d1xkka_ |
| not modelled | 100.0 | 42 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
98 | c1xkkA_ |
| not modelled | 100.0 | 42 | PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
99 | c3ps5A_ |
| not modelled | 100.0 | 26 | PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6; PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
100 | c2x4fA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:myosin light chain kinase family member 4; PDBTitle: the crystal structure of the human myosin light chain2 kinase loc340156.
101 | c2ya9A_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:death-associated protein kinase 2; PDBTitle: crystal structure of the autoinhibited form of mouse dapk2
102 | c2vd5A_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:dmpk protein; PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii
103 | c2b3oA_ |
| not modelled | 100.0 | 26 | PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
104 | c2chlA_ |
| not modelled | 100.0 | 18 | PDB header:transferase Chain: A: PDB Molecule:casein kinase i isoform gamma-3; PDBTitle: structure of casein kinase 1 gamma 3
105 | c2r7bA_ |
| not modelled | 100.0 | 23 | PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
106 | c3comB_ |
| not modelled | 100.0 | 26 | PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase 4; PDBTitle: crystal structure of mst1 kinase
107 | d1uu3a_ |
| not modelled | 100.0 | 23 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
108 | c2r5tA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase sgk1; PDBTitle: crystal structure of inactive serum and glucocorticoid-2 regulated kinase 1 in complex with amp-pnp
109 | c1zrzA_ |
| not modelled | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:protein kinase c, iota; PDBTitle: crystal structure of the catalytic domain of atypical2 protein kinase c-iota
110 | d1rjba_ |
| not modelled | 100.0 | 36 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
111 | d1koba_ |
| not modelled | 100.0 | 22 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
112 | d1o6la_ |
| not modelled | 100.0 | 23 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
113 | c1kobB_ |
| not modelled | 100.0 | 22 | PDB header:kinase Chain: B: PDB Molecule:twitchin; PDBTitle: twitchin kinase fragment (aplysia), autoregulated protein2 kinase domain
114 | c3brbB_ |
| not modelled | 100.0 | 37 | PDB header:transferase Chain: B: PDB Molecule:proto-oncogene tyrosine-protein kinase mer; PDBTitle: crystal structure of catalytic domain of the proto-oncogene tyrosine-2 protein kinase mer in complex with adp
115 | c2y94A_ |
| not modelled | 100.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit alpha-1; PDBTitle: structure of an active form of mammalian ampk
116 | d1koaa2 |
| not modelled | 100.0 | 22 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
117 | c2h6dA_ |
| not modelled | 100.0 | 26 | PDB header:signaling protein,transferase Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit PDBTitle: protein kinase domain of the human 5'-amp-activated protein2 kinase catalytic subunit alpha-2 (ampk alpha-2 chain)
118 | d1fota_ |
| not modelled | 100.0 | 25 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
119 | c2c47D_ |
| not modelled | 100.0 | 18 | PDB header:transferase Chain: D: PDB Molecule:casein kinase 1 gamma 2 isoform; PDBTitle: structure of casein kinase 1 gamma 2
120 | c3kl8C_ |
| not modelled | 100.0 | 21 | PDB header:transferase/ transferase inhibitor Chain: C: PDB Molecule:calcium/calmodulin dependent protein kinase ii; PDBTitle: camkiintide inhibitor complex

Binding site prediction |

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