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Job DescriptionA0AV02
Confidence7.63%DateWed Jun 6 09:26:36 BST 2012
Rank33Aligned Residues356
% Identity12%Templatec3uonA_
PDB info PDB header:signaling protein/antagonistChain: A: PDB Molecule:human m2 muscarinic acetylcholine, receptor t4 lysozyme PDBTitle: structure of the human m2 muscarinic acetylcholine receptor bound to2 an antagonist
Resolution3.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240.........250.........260. ........270.........280.........290.........300.........310.
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Query Sequence  FFTVFGVFFPAATGVMAGFNMGGDLREPA. ASIPPGSLAAVGISWFLYIIFVFLLGAICTREALRYDFLIAEKVSLMGFL
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Template Sequence  FIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM. . . . . . NLYTLYTVIGYWPLGPVVCDL
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GGG
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   25....30.........40.........50.........60.........70....... ..80.........90........
 
   312.......320.........330.........340.........350.........360.........370........
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Query Sequence  FLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVG. . . . . . . . . . . . .
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Template Sequence  WLALDYVVSNASVMNLLIISFDRYFCVTK. . . . PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDG
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   99100.........110.........120....... ..130.........140.........150.........160.........170....
 
   379380.........390.........400.........410.........420.........430.........440.........450
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Query Sequence  . . . . . . . . QVNVLAPIVTINFMLTYVAVDYSYFSLSMCSCSLTPVPEPVLREGAEGLHCSEHLLLEKAPSYGSEGPAQRV
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Template Sequence  ECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPS
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GGGGSTTT


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   175....180.........190.........200.........210.........220.........230.........240.........250....
 
   451........460.........470.........480.........490.........500.........510.........520.........530
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Query Sequence  LEGTLLEFTKDMDQLLQLTRKLESSQPRQGEGNRTPESQKRKSKKATKQTLQDSFLLDLKSPPSFPVEISDRLPAASWEG
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Template Conservation                                                                               .  
Template Sequence  LNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFT. NS
Template Known Secondary structure  SS

TTB

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TTTS
GGG.
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   10391040.........1050.........1060.........1070.........1080.........1090.........1100.........1110..... ..
 
   531........540.........550.........560.........570.........580.........590.........600.........610
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Query Sequence  QESCWNKQTSKSEGTQPEGTYGEQLVPELCNQSESSGEDFFLKSRLQEQDVWRRSTSFYTHMCNPWVSLLGAVGSLLIMF
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Template Sequence  LRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYPPPSREKKV. . . . . . . . . . . . . . . . TRTILAILLAF
Template Known Secondary structure  TT
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   1118.1120.........1130.........1140.........1150.........1160.........1170 .........1180.
 
   611....
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Query Sequence  VIQWV
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Template Sequence  IITWA
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   397..400.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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