|   |   |
191 | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | |
|
. | . | . | . | 220 | . | . | . | . | . | |
|
. | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | M | K | E | L | K | L | L | Q | T | I | G | K | G | E | F | G | D | V | M | L | G | D | Y | R | . |
. |
G | N | K | V | A | V | K | C | I | K | . |
. |
N | D | A | T | A | Q | A | F | L | A | E | A | S | V | M | T | Q | L | R | H | S | N | L | V | Q | L | L | G | V | I | V | E | E | K | G | G | L | Y | I | V | T |
| Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . | . |   |   |   |
|
|
|
|   |   |   | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |
|
|   |
| Template Sequence |   |
P | K | K | K | Y | T | R | F | E | K | I | G | Q | G | A | S | G | T | V | Y | T | A | M | D | V | A | T | G | Q | E | V | A | I | R | Q | M | N | L | Q | Q | Q | P | K | K | E | L | I | I | N | E | I | L | V | M | R | E | N | K | N | P | N | I | V | N | Y | L | D | S | Y | L | V | G | D | . |
E | L | W | V | V | M |
| Template Known Secondary structure |   |
T | T | T | T | B |
| S |
|  |  |
|
|
| S | S | S |
|  |  |  |  |  |  | B | T | T | T |
|
|  |  |  |  |  |  |  |  | G | G | G |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  | T | T | . |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | |
. | 340 | . | . | . | . |
|   |
|   |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
|
|
. | . | 340 | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . |
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
| Query Sequence |   |
E | Y | M | A | K | G | S | L | V | D | Y | L | R | S | R | G | R | S | V | L | G | G | D | C | L | L | K | F | S | L | D | V | C | E | A | M | E | Y | L | E | G | N | N | F | V | H | R | D | L | A | A | R | N | V | L | V | S | E | D | N | V | A | K | V | S | D | F | G | L | T | K | . |
. |
. |
E | A | S | S | T | Q |
| Query Conservation |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   | . | . | . |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | Y | L | A | G | G | S | L | T | D | V | V | T | E | T | C | . |
. |
. |
M | D | E | G | Q | I | A | A | V | C | R | E | C | L | Q | A | L | E | F | L | H | S | N | Q | V | I | H | R | D | I | K | S | D | N | I | L | L | G | M | D | G | S | V | K | L | T | D | F | G | F | C | A | Q | I | T | P | E | Q | S | K | R |
| Template Known Secondary structure |   |
 |
|
| T | T |
| B |  |  |  |  |  |  |  | S |
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T |
|  |  |
|
| S | T | T |
|
| B |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
345 | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | |
|
|
. | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . |
|   |
|   |   |
344 | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | |
|
. | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | T | G | K | L | P | V | K | W | T | A | P | E | A | L | R | E | K | K | F | S | T | K | S | D | V | W | S | F | G | I | L | L | W | E | I | Y | S | F | G | R | V | P | Y | P | R | I | P | L | K | D | V | V | P | R | V | E | K | G | Y | . |
. |
K | M | D | A | P | D | G | C | P | P | A | V | Y | E | V | M | K | N |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   | . | . |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
| Template Sequence |   |
S | T | M | V | G | T | P | Y | W | M | A | P | E | V | V | T | R | K | A | Y | G | P | K | V | D | I | W | S | L | G | I | M | A | I | E | M | I | E | . |
G | E | P | P | Y | L | N | E | N | P | L | R | A | L | Y | L | I | A | T | N | G | T | P | E | L | Q | N | P | E | K | L | S | A | I | F | R | D | F | L | N | R |
| Template Known Secondary structure |   |
|
|
|
| S |
| G | G | G |
|
|  |  |  |  | S | S | S |
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |
| S |
|
|
| S | S | G | G | G | S |
|  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
422 | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 |
|   |
|   |   |
422 | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
C | W | H | L | D | A | A | M | R | P | S | F | L | Q | L | R | E |
| Query Conservation |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
C | L | D | M | D | V | E | K | R | G | S | A | K | E | L | L | Q |
| Template Known Secondary structure |   |
 | T |
| S | S | T | T | T | S |
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
501 | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . |
|   |