Job Description P41240 Confidence 100.00% Date Thu Apr 26 09:28:47 BST 2012 Rank 63 Aligned Residues 254 % Identity 39% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

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		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.							.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.				.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.		.
Predicted Secondary structure																													.	.	.	.	.	.																		.	.	.																										.
Query SS confidence																													.	.	.	.	.	.																		.	.	.																										.
Query Sequence		A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L	G	D	Y	R	.	.	.	.	.	.	G	N	K	V	A	V	K	C	I	K	N	D	A	T	A	Q	A	.	.	.	F	L	A	E	A	S	V	M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	.	E
Query Conservation																													.	.	.	.	.	.																		.	.	.																										.
Alig confidence																													.	.	.	.	.	.																		.	.	.																										.
Template Conservation
Template Sequence		V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	H	R	S	G	W	K	Q	E	I	D	I	L	R	T	L	Y	H	E	H	I	I	K	Y	K	G	C	C	E	D	A	G
Template Known Secondary structure					G	G	G											S	S										T	T	S	S	S												S	S																						T	T	B										T	T
Template Predicted Secondary structure
Template SS confidence
		891	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970
		259	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.
Predicted Secondary structure																																																																																	.
Query SS confidence																																																																																	.
Query Sequence		K	G	G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A	A	R	N	V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	.
Query Conservation																																																																																	.
Alig confidence																										.	.	.																																																					.
Template Conservation																										.	.	.
Template Sequence		A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	H	S	.	.	.	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A
Template Known Secondary structure		T	T										T	T		B					G	G	G	S		.	.	.																							T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure																										.	.	.
Template SS confidence
		971	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.				.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.
			338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.																.	390	.	.	.	.	.	.	.	.	.	400	.
Predicted Secondary structure		.																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	E	A	S	S	T	Q	D	T	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	I	P	L	K	D	V	V	P	R	V	E	K
Query Conservation		.																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.																																													.							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																															.
Template Sequence		V	P	E	G	H	E	Y	R	V	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	A	Q	G	Q	M	T	V	L	R	L	T	E	L	L	E	R
Template Known Secondary structure				T	T				B						G	G	G								S		B																			T	.	T	T		G	G	G	S											S	T	T	G	G	G											T
Template Predicted Secondary structure																																															.
Template SS confidence
		1048	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.
		402	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	Y	K	M	D	A	P	D	G	C	P	P	A	V	Y	E	V	M	K	N	C	W	H	L	D	A	A	M	R	P	S	F	L	Q	L	R	E	Q	L	E	H	I	K	T	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	E	R	L	P	R	P	D	K	C	P	A	E	V	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	E	N	L	I	P	I	L	K	T	V	H	E	K
Template Known Secondary structure		T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1131	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions