Return to main results Retrieve Phyre Job Id

Job DescriptionP41240
Confidence100.00%DateThu Apr 26 09:28:47 BST 2012
Rank82Aligned Residues241
% Identity45%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   186...190.........200.........210..... ....220.........230.........240.........250.........260....
Predicted Secondary structure 













.













Query SS confidence 





























.
















































Query Sequence  SGWALNMKELKLLQTIGKGEFGDVMLGDYR. GNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYI
Query Conservation     

      
   

 
 

 
      .   



          
  
   
  
 




 
 
        
 
Alig confidence 





























.










......






















.







Template Conservation      
          

 
 

 
 
        



 

 ......   

  
  
 




      .        
Template Sequence  GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKE. . . . . . FIEEAKVMMNLSHEKLVQLYGVC. TKQRPIFI
Template Known Secondary structure  GGGB

GGGSTTSS
TTT


......
TT


TTB

.
SSSS
Template Predicted Secondary structure 









......











.





Template SS confidence 















































































   393......400.........410.........420.........430.... .....440.........450....... ..460.....
 
   265....270.........280.........290.........300.........310.........320.........330.........340....
Predicted Secondary structure 










































Query SS confidence 















































































Query Sequence  VTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQD
Query Conservation 
 
    
 
   
       
          


 

 


    

 

   


       

 




        
Alig confidence 



















.


















































........
Template Conservation 
        
          .                                            
 
    ........
Template Sequence  ITEYMANGCLLNYLREMRHR. FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . . .
Template Known Secondary structure 

TT
GGG
.

TT


S

SGGG
TT







........
Template Predicted Secondary structure 
















.























........
Template SS confidence 















































































   473......480.........490.. .......500.........510.........520.........530.........540...
 
   345....350.........360.........370.........380.........390.........400.........410.........420....
Predicted Secondary structure 

































Query SS confidence 















































































Query Sequence  TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWH
Query Conservation           


       
 








 
 

 
 
  

      

   
  
 
   
   
  
  

  
  
Alig confidence  .....










































































Template Conservation  .....                  

 
 
    

 
                 
            
     

  

 
Template Sequence  . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWH
Template Known Secondary structure  .....GGG





TTS

TTTTS
TT





TTS
TT
Template Predicted Secondary structure  .....













































Template SS confidence 















































































   561........570.........580.........590.........600.........610.........620.........630.....
 
   425....430.........440.......
Predicted Secondary structure 




Query SS confidence 






















Query Sequence  LDAAMRPSFLQLREQLEHIKTHE
Query Conservation   

  


   
   
  
    
Alig confidence 






















Template Conservation   

  


  


  
  

   
Template Sequence  EKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  SSGGGS


Template Predicted Secondary structure 






Template SS confidence 






















   636...640.........650........
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions