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Job DescriptionP41240
Confidence100.00%DateThu Apr 26 09:28:47 BST 2012
Rank182Aligned Residues235
% Identity26%Templatec3fmeA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6; PDBTitle: crystal structure of human mitogen-activated protein kinase kinase 62 (mek6) activated mutant (s207d, t211d)
Resolution2.26 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   189190.........200.........210..... ....220.........230........ .240.........250.........260.....
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Query Sequence  ALNMKELKLLQTIGKGEFGDVMLGDYR. . GNKVAVKCIKNDATAQAFLAEAS. VMTQLRHSNLVQLLGVIVEEKGGLYIV
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Template Sequence  EVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRNSQEQKRLLMDLDISMRTVDCPFTVTFYGAL. FREGDVWIC
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   47..50.........60.........70.........80.........90.........100.........110...... ...120.....
 
   266...270......... 280.........290.........300........ .310.........320.........330.........340...
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Query Sequence  TEYMAKGSLVDYLR. SRGRSVLGGDCLLKFSLDVCEAMEYLEGN. NFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQ
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Template Sequence  MELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFA. . . . . . . . .
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   129130.........140.........150.........160.........170.........180.........190.........
 
   344.....350.........360 .........370.........380.........390. ........400.........410.........
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Query Sequence  DTGKLPVKWTAPEALRE. . KKFSTKSDVWSFGILLWEIYSFGRVPYPRIP. . LKDVVPRVEKGYKMDAPDGCPPAVYEVM
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Template Sequence  . . . . GCKPYMAPERINPELNQYSVKSDIWSLGITMIELAI. LRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFT
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   215....220.........230.........240.........250 .........260.........270.........280.........
 
   420.........430........
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Query Sequence  KNCWHLDAAMRPSFLQLRE
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Template Sequence  SQCLKKNSKERPTYPELMQ
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   292.......300.........310
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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