Job Description P41240 Confidence 100.00% Date Thu Apr 26 09:28:47 BST 2012 Rank 50 Aligned Residues 254 % Identity 35% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		186	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.							.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																.	.	.	.	.	.
Query SS confidence																																.	.	.	.	.	.
Query Sequence		S	G	W	A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L	G	D	Y	R	.	.	.	.	.	.	G	N	K	V	A	V	K	C	I	K	N	D	A	T	A	Q	A	F	L	A	E	A	S	V	M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K
Query Conservation																																.	.	.	.	.	.
Alig confidence																																.	.	.	.	.	.											.	.
Template Conservation																																																.	.
Template Sequence		D	P	T	H	F	E	K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	.	.	P	H	I	A	D	L	K	K	E	I	E	I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	G	I	C	T	E	N	G
Template Known Secondary structure			T	T	S			G	G	G											S	S										T	T	S	S	S		S										.	.															T				T	T	B
Template Predicted Secondary structure																																																.	.
Template SS confidence
		866	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.			.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.
		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.
Predicted Secondary structure																																																																																.	.
Query SS confidence																																																																																.	.
Query Sequence		G	G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A	A	R	N	V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	.	.
Query Conservation																																																																																.	.
Alig confidence		.	.																								.																																																					.	.
Template Conservation		.	.																								.
Template Sequence		.	.	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	.	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A	I
Template Known Secondary structure		.	.									T	T		B					T	G	G	G	T	T	T	.																							T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure		.	.																								.
Template SS confidence
				952	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.		.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.
				338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.																.	.	390	.	.	.	.	.	.	.	.	.	400
Predicted Secondary structure		.	.																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	E	A	S	S	T	Q	D	T	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	R	I	P	L	K	D	V	V	P	R	V	E
Query Conservation		.	.																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.																																													.						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																.
Template Sequence		E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A	P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	.	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T	R	L	V	N	T	L	K
Template Known Secondary structure			T	T					S			T	T			G	G	G																													T	.	T	T		G	G	G												S			G	G	G
Template Predicted Secondary structure																																																.
Template SS confidence
		1029	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.		.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	G	Y	K	M	D	A	P	D	G	C	P	P	A	V	Y	E	V	M	K	N	C	W	H	L	D	A	A	M	R	P	S	F	L	Q	L	R	E	Q	L	E	H	I	K	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L	L	K
Template Known Secondary structure		T	T							T	T												T			S	S	G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions