|   |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | |
|
. | . | . | . | 220 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
W | A | L | N | M | K | E | L | K | L | L | Q | T | I | G | K | G | E | F | G | D | V | M | L | G | D | Y | R | . |
. |
G | N | K | V | A | V | K | C | I | . |
. |
. |
. |
. |
K | N | D | A | T | A | Q | A | F | L | A | E | A | S | V | M | T | Q | L | R | H | S | N | L | V | Q | L | L | G | V | I | V | E | E | K | G |
| Query Conservation |   |
  |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . | . |   |   |   |
|
|
|
|   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|   |
|
|   |
|   |   |   |   | . |   |   |   |   |
| Template Sequence |   |
Q | P | M | G | E | D | W | F | L | D | F | R | V | L | G | R | G | G | F | G | E | V | F | A | C | Q | M | K | A | T | G | K | L | Y | A | C | K | K | L | N | K | K | R | L | K | K | R | K | G | Y | Q | G | A | M | V | E | K | K | I | L | A | K | V | H | S | R | F | I | V | S | L | A | Y | A | F | . |
E | T | K | T |
| Template Known Secondary structure |   |
S |
|
|
| G | G | G | B |
|
|
|  |  |
|
|
| S | S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
| B |
|  |  |  | . |  |
| S | S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
. | . | . | . |
|   |
|   |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | |
|
. | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| Query Sequence |   |
G | L | Y | I | V | T | E | Y | M | A | K | G | S | L | V | D | Y | L | R | S | . |
. |
R | G | R | S | V | L | G | G | D | C | L | L | K | F | S | L | D | V | C | E | A | M | E | Y | L | E | G | N | N | F | V | H | R | D | L | A | A | R | N | V | L | V | S | E | D | N | V | A | K | V | S | D | F | G | L | T | K | . |
| Query Conservation |   |
  |
|   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| Template Conservation |   |
  |   |   |
|
|   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |
| Template Sequence |   |
D | L | C | L | V | M | T | I | M | N | G | G | D | I | R | Y | H | I | Y | N | V | D | E | D | N | P | G | F | Q | E | P | R | A | I | F | Y | T | A | Q | I | V | S | G | L | E | H | L | H | Q | R | N | I | I | Y | R | D | L | K | P | E | N | V | L | L | D | D | D | G | N | V | R | I | S | D | L | G | L | A | V | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  |
|
|
|
| S |  |  |  |  |  |  |  | T | T | T | S | S | S | S |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | B |
|
|
|
|
|
| G | G | G |  |  |  |
| S | S | S |
|  |  |  |
|
|
| S | S |
|
| B |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
|   |
|   |   |
|
|
338 | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | |
|
. | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . |
| Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |
| Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
E | A | S | S | T | Q | D | T | G | K | L | P | V | K | W | T | A | P | E | A | L | R | E | K | K | F | S | T | K | S | D | V | W | S | F | G | I | L | L | W | E | I | Y | S | F | G | R | V | P | Y | P | R | I | . |
. |
P | L | K | D | V | V | P | R | V | E | K | G | Y | K | M | D | A | P | D | G | C | P | P |
| Query Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |   | . | . |   |   |   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . |   |   |   |
|   |   |   |
|   |
| Template Sequence |   |
L | K | A | G | Q | T | K | T | K | G | Y | A | G | T | P | G | F | M | A | P | E | L | L | L | G | E | E | Y | D | F | S | V | D | Y | F | A | L | G | V | T | L | Y | E | M | I | A | . |
A | R | G | P | F | R | A | R | G | V | E | N | K | E | L | K | Q | R | V | L | E | Q | A | . |
V | T | Y | P | D | K | F | S | P |
| Template Known Secondary structure |   |
|
| S | S |
|
|
| B |
|
|
|
| S |
| T | T | T | S |
|  |  |  |  | T | T |
|
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | S | S |
| S | S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  | T |
|
| . |
|
|
|
| S | S |
|
|  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
339 | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | |
. | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | |
. | . | 410 | . | . | . | . | . | . |
|   |
|   |   |
414 | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | |
|
|
|
|
. | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
| . | . | . | . | . |
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | V | Y | E | V | M | K | N | C | W | H | L | D | A | A | M | R | . |
. |
. |
. |
. |
P | S | F | L | Q | L | R | E |
| Query Conservation |   |
  |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
| . | . | . | . | . |
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |
| Template Sequence |   |
A | S | K | D | F | C | E | A | L | L | Q | K | D | P | E | K | R | L | G | F | R | D | G | S | C | D | G | L | R | T |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |
| S | S | S | S | S | S |
|
| S |
| T | T | S | T | T | T | T | T | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
419 | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . |
|   |