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Job DescriptionP41240
Confidence100.00%DateThu Apr 26 09:28:47 BST 2012
Rank194Aligned Residues246
% Identity39%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  SGWALNMKE. . LKLLQTIGKGEFGDVMLGDY. . . . . RGNKVAVKCIKNDATAQA. . . FLAEASVMTQLRHSNLVQLLGVI
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Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC
Template Known Secondary structure  TTTB

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   1067..1070.........1080.........1090.........1100.........1110.........1120.........1130.........1140......
 
   256...260.........270.........280.........290.........300.........310.........320.........330.....
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Query Sequence  VEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGL
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Template Sequence  LRSEGSPLVVLPYMKHGDLRNFIRNETHN. PTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADFL.
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   1147..1150.........1160.........1170..... ....1180.........1190.........1200.........1210.........1220....
 
   336...340.........350.........360.........370.........380.........390.........400.........410.....
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Query Sequence  TKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAV
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Template Sequence  . . . . . . . . . . . . . PVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPL
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   1246...1250.........1260.........1270.........1280.........1290.........1300.........1310..
 
   416...420.........430.........440......
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Query Sequence  YEVMKNCWHLDAAMRPSFLQLREQLEHIKTH
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Template Sequence  YEVMLKCWHPKAEMRPSFSELVSRISAIFST
Template Known Secondary structure  T
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   1313......1320.........1330.........1340...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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