Job Description P41240 Confidence 100.00% Date Thu Apr 26 09:28:47 BST 2012 Rank 170 Aligned Residues 257 % Identity 35% Template c2xbaA_ PDB info PDB header:transferase Chain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429 Resolution 1.95 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		188	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.					.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.				.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
Predicted Secondary structure																					.	.	.	.																				.	.	.
Query SS confidence																					.	.	.	.																				.	.	.
Query Sequence		W	A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	.	.	.	.	G	D	V	M	L	G	D	Y	R	G	N	K	V	A	V	K	C	I	K	.	.	.	N	D	A	T	A	Q	A	F	L	A	E	A	S	V	M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K	G
Query Conservation																					.	.	.	.																				.	.	.
Alig confidence																					.	.	.	.																				.	.	.
Template Conservation
Template Sequence		F	A	G	K	T	S	S	I	S	D	L	K	E	V	P	R	K	N	I	T	L	I	R	G	L	V	Y	E	G	Q	V	S	P	L	Q	V	A	V	K	T	L	P	E	V	C	S	E	Q	D	E	L	D	F	L	M	E	A	L	I	I	S	K	F	N	H	Q	N	I	V	R	C	I	G	V	S	L	Q	S	L	P
Template Known Secondary structure			T	T					G	G	G	S		B			G	G	G																									S	S																						T	T	B									S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		1098	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280						.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.
Predicted Secondary structure																						.	.	.	.	.
Query SS confidence																						.	.	.	.	.
Query Sequence		G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	.	.	.	.	.	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A	A	R	N	V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L
Query Conservation																						.	.	.	.	.
Alig confidence			.																			.	.	.	.	.
Template Conservation			.
Template Sequence		R	.	F	I	L	L	E	L	M	A	G	G	D	L	K	S	F	L	R	E	T	R	P	R	P	S	Q	P	S	S	L	A	M	L	D	L	L	H	V	A	R	D	I	A	C	G	C	Q	Y	L	E	E	N	H	F	I	H	R	D	I	A	A	R	N	C	L	L	T	C	P	G	P	G	R	V	A	K	I	G	D
Template Known Secondary structure			.								T	T											S		B	T	T	B	T	T	S																							T	T				S				G	G	G				S		S	S	T	T
Template Predicted Secondary structure			.
Template SS confidence
		1192		.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270
		336	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	K	E	A	S	S	T	Q	D	T	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P	L	K	D	V	V	P	R	V	E	K	G	Y	K	M	D	A	P	D	G	C	P	P	A	V
Query Conservation
Alig confidence													.	.
Template Conservation													.	.
Template Sequence		F	G	M	A	R	D	I	Y	A	M	L	.	.	P	V	K	W	M	P	P	E	A	F	M	E	G	I	F	T	S	K	T	D	T	W	S	F	G	V	L	L	W	E	I	F	S	L	G	Y	M	P	Y	P	S	K	S	N	Q	E	V	L	E	F	V	T	S	G	G	R	M	D	P	P	K	N	C	P	G	P	V
Template Known Secondary structure												S	.	.		G	G	G								T																					T	T	S			S	S	T	T												T	T							T	T
Template Predicted Secondary structure													.	.
Template SS confidence
		1271	.	.	.	.	.	.	.	.	1280	.			.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.
		416	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	E	V	M	K	N	C	W	H	L	D	A	A	M	R	P	S	F	L	Q	L	R	E	Q	L	E	H	I	K	T	H	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	R	I	M	T	Q	C	W	Q	H	Q	P	E	D	R	P	N	F	A	I	I	L	E	R	I	E	Y	C	T	Q	D	P
Template Known Secondary structure									T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1359	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions