Job Description P41240 Confidence 100.00% Date Thu Apr 26 09:28:47 BST 2012 Rank 61 Aligned Residues 253 % Identity 37% Template c2w1iB_ PDB info PDB header:transferase Chain: B: PDB Molecule:jak2; PDBTitle: structure determination of aurora kinase in complex with2 inhibitor Resolution 2.60 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.							.	.	.	.	220	.	.	.	.	.	.	.	.	.	230			.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
Predicted Secondary structure																													.	.	.	.	.	.																.	.
Query SS confidence																													.	.	.	.	.	.																.	.
Query Sequence		A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L	G	D	Y	R	.	.	.	.	.	.	G	N	K	V	A	V	K	C	I	K	N	D	A	T	A	.	.	Q	A	F	L	A	E	A	S	V	M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K	G
Query Conservation																													.	.	.	.	.	.																.	.
Alig confidence																													.	.	.	.	.	.																.	.																														.
Template Conservation																																																																																	.
Template Sequence		Q	F	E	E	R	H	L	K	F	L	Q	Q	L	G	K	G	N	F	G	S	V	E	M	C	R	Y	D	P	L	Q	D	N	T	G	E	V	V	A	V	K	K	L	Q	H	S	T	E	E	H	L	R	D	F	E	R	E	I	E	I	L	K	S	L	Q	H	D	N	I	V	K	Y	K	G	V	C	Y	S	N	L	.
Template Known Secondary structure					G	G	G											T	T										S	S		S	S											S	S			S																			T	T	B												.
Template Predicted Secondary structure																																																																																	.
Template SS confidence
		843	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.
Predicted Secondary structure																																																																															.	.	.
Query SS confidence																																																																															.	.	.
Query Sequence		G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A	A	R	N	V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	.	.	.
Query Conservation																																																																															.	.	.
Alig confidence		.	.																							.																																																					.	.	.
Template Conservation		.	.																							.
Template Sequence		.	.	K	L	I	M	E	Y	L	P	Y	G	S	L	R	D	Y	L	Q	K	H	K	E	R	.	I	D	H	I	K	L	L	Q	Y	T	S	Q	I	C	K	G	M	E	Y	L	G	T	K	R	Y	I	H	R	D	L	A	T	R	N	I	L	V	E	N	E	N	R	V	K	I	G	D	F	G	L	T	K	V	L	P
Template Known Secondary structure		.	.								T	T		B								T	T	T	T	.	S																						T	T				S				G	G	G						T	T								T	T
Template Predicted Secondary structure		.	.																							.
Template SS confidence
				926	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.		.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.
			338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.																	390	.	.	.	.	.	.	.	.	.	400
Predicted Secondary structure		.																																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.																																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	E	A	S	S	T	Q	D	T	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	P	L	K	D	V	V	P	R	V	E
Query Conservation		.																																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.																																													.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																															.
Template Sequence		Q	D	K	E	K	V	K	E	P	G	E	S	P	I	F	W	Y	A	P	E	S	L	T	E	S	K	F	S	V	A	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	I	E	K	S	K	S	P	P	A	E	F	M	R	M	I	G	N	D	K	Q	G	Q	M	I	V	F	H	L	I	E	L	L	K
Template Known Secondary structure		T	T					S	S			S			G	G	G																														.	T	T		G	G	G	S											T	T			S
Template Predicted Secondary structure																																															.
Template SS confidence
		1003	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.		.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	G	Y	K	M	D	A	P	D	G	C	P	P	A	V	Y	E	V	M	K	N	C	W	H	L	D	A	A	M	R	P	S	F	L	Q	L	R	E	Q	L	E	H	I	K	T	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	N	G	R	L	P	R	P	D	G	C	P	D	E	I	Y	M	I	M	T	E	C	W	N	N	N	V	N	Q	R	P	S	F	R	D	L	A	L	R	V	D	Q	I	R	D	Q
Template Known Secondary structure		T	T							T	T													S		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1084	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions