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Job DescriptionP41240
Confidence100.00%DateThu Apr 26 09:28:47 BST 2012
Rank256Aligned Residues248
% Identity26%Templatec2vagA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity protein kinase clk1; PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor
Resolution1.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  ALNMKELKLLQTIGKGEFGDVMLGDYR. . . GNKVAVKCIKNDATA. QAFLAEASVMTQLRHSNLVQLLGV. . . . . IVEEK
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Template Sequence  DVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHH
Template Known Secondary structure 
TTTTTTTTTT
SS
TT
TT
B

T
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   155....160.........170.........180.........190.........200.........210.........220.........230....
 
   260.........270.........280.........290.........300.........310.........320.........330.........
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Query Sequence  GGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEA
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Template Sequence  GHICIVFELL. GLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNKRDERTL
Template Known Secondary structure  T

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   235....240.... .....250.........260.........270.........280.........290.........300.........310...
 
   340...... ...350.........360.........370.........380.........390.........400.
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Query Sequence  SSTQDTG. . . . . . . . . . . . . . KLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK. . . .
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Template Sequence  INPDIKVVDFGSATYDDEHHSTLVRHYRAPEVILALGWSQPCDVWSIGCILIEYYL. GFTVFPTHDSKEHLAMMERILGP
Template Known Secondary structure  S





SS
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S

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   317..320.........330.........340.........350.........360.........370.. .......380.........390.....
 
   402.......410.........420.........430........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLRE
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Template Sequence  LPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALK
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S
GGGTT


TTS


GGGG
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ST
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TT
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   398.400.........410.........420.........430.........440.........450.........460.........470...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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