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Job DescriptionP41240
Confidence100.00%DateThu Apr 26 09:28:47 BST 2012
Rank79Aligned Residues245
% Identity26%Templatec2j51A_
PDB info PDB header:transferaseChain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
Resolution2.1 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   191........200.........210..... ....220.... .....230.........240.........250.........260......
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Query Sequence  NMKELKLLQTIGKGEFGDVMLGDYR. . GNKVAVKCI. . KNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVT
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Template Sequence  PEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYEN. NLWILI
Template Known Secondary structure  GGGTTTTTT


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   30.........40.........50.........60.........70.........80.........90.........100.. ......
 
   267..270.........280.........290.........300.........310.........320.........330....... ..340...
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Query Sequence  EYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK. . . EASSTQ
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Template Sequence  EFCAGGAVDAVMLELERP. LTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR
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SGGG
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   109110.........120...... ...130.........140.........150.........160.........170.........180.......
 
   344.....350........ .360.........370.........380.........390.........400... ......410......
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Query Sequence  DTGKLPVKWTAPEAL. . . . . REKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGY. . KMDAPDGCPPAVY
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Template Sequence  DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE. IEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFK
Template Known Secondary structure  S


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   188.190.........200.........210.........220.........230 .........240.........250.........260......
 
   417..420.........430........
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Query Sequence  EVMKNCWHLDAAMRPSFLQLRE
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Template Sequence  DFLKKCLEKNVDARWTTSQLLQ
Template Known Secondary structure  S
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   267..270.........280........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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