Job Description P41240 Confidence 100.00% Date Thu Apr 26 09:28:47 BST 2012 Rank 6 Aligned Residues 413 % Identity 40% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å

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		13	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.		.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Predicted Secondary structure																																										.
Query SS confidence																																										.
Query Sequence		E	C	I	A	K	Y	N	F	H	G	T	A	E	Q	D	L	P	F	C	K	G	D	V	L	T	I	V	A	V	T	K	D	P	N	W	Y	K	A	K	N	.	K	V	G	R	E	G	I	I	P	A	N	Y	V	Q	K	R	E	G	V	K	A	G	T	K	L	S	L	M	P	W	F	H	G	K	I	T	R	E	Q
Query Conservation																																										.
Alig confidence																																		.	.							.																			.	.	.	.	.	.
Template Conservation																																		.	.																										.	.	.	.	.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	S	G	E	.	.	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	.	.	.	.	.	.	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T										T	T	.	.							T	T	T								G	G	G				T	T	S	.	.	.	.	.	.	G	G	G	S	T	T			T	T
Template Predicted Secondary structure																																		.	.																										.	.	.	.	.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.			.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.							.	.	120	.	.	.	.	.	.	.	.	.	130	.	.
		92	.	.	.	.			.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.						.	.	.	.	.	.	.	.	130	.	.	.	.		.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.
Predicted Secondary structure							.	.																										.	.	.	.	.														.
Query SS confidence							.	.																										.	.	.	.	.														.
Query Sequence		A	E	R	L	L	.	.	Y	P	P	E	T	G	L	F	L	V	R	E	S	T	N	Y	P	G	D	Y	T	L	C	V	S	.	.	.	.	.	C	D	G	K	V	E	H	Y	R	I	M	Y	H	.	A	S	K	L	S	I	D	E	E	V	Y	F	E	N	L	M	Q	L	V	E	H	Y	T	S	D	A	D	G	L
Query Conservation							.	.																										.	.	.	.	.														.
Alig confidence							.	.																										.	.	.	.	.														.
Template Conservation
Template Sequence		A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L
Template Known Secondary structure							T	S	T	T			T	T								S	S	S	T	T											T	T	T										B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S
Template Predicted Secondary structure
Template SS confidence
		133	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.		.	.	.	.	220	.	.	.	.	.	.	.	.	.	230		.	.	.	.	.	.	.	.	.	240	.
Predicted Secondary structure																																																						.																.
Query SS confidence																																																						.																.
Query Sequence		C	T	R	L	I	K	P	K	V	M	E	G	T	V	A	A	Q	D	E	F	Y	R	S	G	W	A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L	G	D	Y	R	.	G	N	K	V	A	V	K	C	I	K	N	D	A	T	A	.	Q	A	F	L	A	E	A	S	V	M	T
Query Conservation																																																						.																.
Alig confidence																.	.	.																																				.																.
Template Conservation																.	.	.
Template Sequence		C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	.	.	.	K	P	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K
Template Known Secondary structure		S	S				S	B								.	.	.					T	T		S	B			G	G	G											T	T									T	T	T												S	S
Template Predicted Secondary structure																.	.	.
Template SS confidence
		213	.	.	.	.	.	.	220	.	.	.	.	.	.				.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K	G	G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A	A	R	N	V	L
Query Conservation
Alig confidence																.	.
Template Conservation																.	.
Template Sequence		T	L	Q	H	D	K	L	V	K	L	H	A	V	V	.	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L
Template Known Secondary structure		T				T	T	B								.	.		S	S	S									T	T		B							S	T	T	G	G	G																							T	T				S			S	G	G	G
Template Predicted Secondary structure																.	.
Template SS confidence
		290	.	.	.	.	.	.	.	.	.	300	.	.	.			.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.
		322	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	E	A	S	S	T	Q	D	T	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P	L	K	D	V	V	P	R	V	E	K
Query Conservation
Alig confidence																				.	.	.	.	.	.	.	.	.
Template Conservation																				.	.	.	.	.	.	.	.	.
Template Sequence		V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	V	I	.	.	.	.	.	.	.	.	.	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R
Template Known Secondary structure				T	T								T	T	G	G	G	T		.	.	.	.	.	.	.	.	.		G	G	G	S																												T	T	T			S	S	T	T												T
Template Predicted Secondary structure																				.	.	.	.	.	.	.	.	.
Template SS confidence
		368	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.										.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.
		402	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	Y	K	M	D	A	P	D	G	C	P	P	A	V	Y	E	V	M	K	N	C	W	H	L	D	A	A	M	R	P	S	F	L	Q	L	R	E	Q	L	E	H	I	K	T	H	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T
Template Known Secondary structure		T							T	T													T		S	S	G	G	G	S												T	T	T	S		G
Template Predicted Secondary structure
Template SS confidence
		452	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.