Job Description P41240 Confidence 100.00% Date Thu Apr 26 09:28:47 BST 2012 Rank 73 Aligned Residues 250 % Identity 35% Template c1xkkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016 Resolution 2.40 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.			.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.
Predicted Secondary structure																												.	.
Query SS confidence																												.	.
Query Sequence		L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L	G	D	Y	R	.	.	G	N	K	V	A	V	K	C	I	K	N	D	A	T	A	Q	A	F	L	A	E	A	S	V	M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K	G	G	L	Y	I	V	T	E
Query Conservation																												.	.
Alig confidence																												.	.												.																																	.	.
Template Conservation																																									.																																	.	.
Template Sequence		L	K	E	T	E	F	K	K	I	K	V	L	G	S	G	A	F	G	T	V	Y	K	G	L	W	I	P	V	K	I	P	V	A	I	K	E	L	R	E	.	K	A	N	K	E	I	L	D	E	A	Y	V	M	A	S	V	D	N	P	H	V	C	R	L	L	G	I	C	L	T	S	T	.	.	V	Q	L	I	T	Q
Template Known Secondary structure				T	T	T											S	S																							.		T																	T	T	B									S	S	S	.	.
Template Predicted Secondary structure																																									.																																	.	.
Template SS confidence
		707	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.		.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.			.	.	780	.	.	.
		268	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A	A	R	N	V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	E	A	S	S	T	Q	D	T	G	K
Query Conservation
Alig confidence																			.																																																													.	.
Template Conservation																			.																																																													.	.
Template Sequence		L	M	P	F	G	C	L	L	D	Y	V	R	E	H	K	D	N	.	I	G	S	Q	Y	L	L	N	W	C	V	Q	I	A	K	G	M	N	Y	L	E	D	R	R	L	V	H	R	D	L	A	A	R	N	V	L	V	K	T	P	Q	H	V	K	I	T	D	F	G	L	A	K	L	L	G	A	E	E	K	V	.	.
Template Known Secondary structure				T	T		B								T	S	S	S	.																							T	T				S				G	G	G						T	T								S					T	T	T	T				.	.
Template Predicted Secondary structure																			.																																																													.	.
Template SS confidence
		792	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.		.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.
		348	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P	L	K	D	V	V	P	R	V	E	K	G	Y	K	M	D	A	P	D	G	C	P	P	A	V	Y	E	V	M	K	N	C	W	H	L	D	A
Query Conservation
Alig confidence		.
Template Conservation		.
Template Sequence		.	P	I	K	W	M	A	L	E	S	I	L	H	R	I	Y	T	H	Q	S	D	V	W	S	Y	G	V	T	V	W	E	L	M	T	F	G	S	K	P	Y	D	G	I	P	A	S	E	I	S	S	I	L	E	K	G	E	R	L	P	Q	P	P	I	C	T	I	D	V	Y	M	I	M	V	K	C	W	M	I	D	A
Template Known Secondary structure		.		T	T	T	S																												T	T	S			T	T	T	T	S		G	G	G								T							T	T	B												T		S	S	G
Template Predicted Secondary structure		.
Template SS confidence
			877	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.
		428	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	M	R	P	S	F	L	Q	L	R	E	Q	L	E	H	I	K	T	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	S	R	P	K	F	R	E	L	I	I	E	F	S	K	M	A	R	D
Template Known Secondary structure		G	G	S																S
Template Predicted Secondary structure
Template SS confidence
		956	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions