|   |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | W | Y | H | G | K | L | D | R | T | I | A | E | E | R | L | R | Q | A | G | K | S | G | S | Y | L | I | R | E | S | D | R | R | P | G | S | F | V | L | S | F | L | S | Q | M | N | V | V | N | H | F | R | I | I | A | M | C | G | D | Y | Y | I | . |
G | G | R | R | F | S | S | L | S | D | L | I | G | Y | Y | S | H |
| Query Conservation |   |
|
|   |
|
|   |
|
|
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|   |
|
|
|
|   |
|   |
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|
|
|   |
|   |
|   |   |
|
|   |
|
|   |   |   |
|   |
|
|   |
|
|
|
|   |
|   |   |   |   |
|   |   |   |
|
|   |   | . |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |   |
|   |   |
| Template Sequence |   |
R | W | F | H | R | D | L | S | G | L | D | A | E | T | L | L | K | G | R | G | V | H | G | S | F | L | A | R | P | S | R | K | N | Q | G | D | F | S | L | S | V | R | . |
V | G | D | Q | V | T | H | I | R | I | Q | N | S | G | D | F | Y | D | L | Y | G | G | E | K | F | A | T | L | T | E | L | V | E | Y | Y | T | Q |
| Template Known Secondary structure |   |
T | T | B |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |
| S | S | S | S | S |  |  |  |  |  |  |  | . |  | T | T |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  | T | T | S |
|  |  | S |
|  |  |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | |
. | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
|   |
|   |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | S | C | L | L | K | G | E | K | L | L | Y | P | V | A | P | P | E | P | V | E | D | R | R | R | V | R | A | I | L | P | Y | T | K | V | P | D | T | D | E | I | S | F | L | K | G | D | M | F | I | V | H | N | E | L | E | D | G | W | M | W | V | T | N | L | R | T | D | E | Q | G | L | I | V | E | D | L | V | E | E |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   | . |   |   |   |
|   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
Q | Q | G | V | L | Q | D | R | D | G | T | . |
I | I | H | L | K | Y | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
T |
| S |
| B |
|
| S | S | S |
| . |
| B |
|
|
|  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
82 | . | . | . | . | . | . | . | 90 | . | . | |
. | . | . | . | . | . | . | 100 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |
339 | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | G | R | E | E | D | P | H | E | G | K | I | W | F | H | G | K | I | S | K | Q | E | A | Y | N | L | L | M | T | V | G | Q | V | C | S | F | L | V | R | P | S | D | N | T | P | G | D | Y | S | L | Y | F | R | T | N | E | N | . |
. |
. |
. |
. |
I | Q | R | F | K | I | C | P | T | P | N | N | Q | F | M | M | G | G |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   | . | . | . | . | . |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|   |
|
|
|   |
|
|   |   |   |   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
| Template Sequence |   |
. |
. |
. |
N | C | S | D | P | T | S | E | R | W | Y | H | G | H | M | S | G | G | Q | A | E | T | L | L | Q | A | K | G | E | P | W | T | F | L | V | R | E | S | L | S | Q | P | G | D | F | V | L | S | V | L | S | D | Q | P | K | S | P | L | R | V | T | H | I | K | V | M | C | E | G | G | R | Y | T | V | G | G | L |
| Template Known Secondary structure |   |
. | . | . |
|
|
|
| G | G | G |
| T | T | B |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |
| S | S | S | T | T |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | B |
|
| T | T | S | B | B | S | S | S | S |
| Template Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
101 | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . |
|   |
|   |   |
414 | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | |
|
|
|
. | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | Y | Y | N | S | I | G | D | I | I | D | H | Y | R | K | E | Q | I | V | E | G | . |
. |
. |
. |
Y | Y | L | K | E | P | V | P | M | Q | D | Q | E | Q | V | L | N | D | T | V | D | G | K | E | I |
| Query Conservation |   |
  |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
| Template Sequence |   |
E | T | F | D | S | L | T | D | L | V | E | H | F | K | K | T | G | I | E | E | A | S | G | A | F | V | Y | L | R | Q | P | Y | Y | A | T | R | V | N | A | A | D | I | E | N | R | F | W | E | E | F |
| Template Known Secondary structure |   |
|
| B | S | S |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
| S | S | S |
|  |  |
|
|
|  |  |
|
|
|
|
|
|
|
| G | G | G | T |
|
|
|  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
182 | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
|   |