Job Description P20936 Confidence 99.97% Date Fri May 25 10:08:08 BST 2012 Rank 11 Aligned Residues 208 % Identity 26% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å

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		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200		.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.			.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.
Predicted Secondary structure																						.																																										.	.
Query SS confidence																						.																																										.	.
Query Sequence		W	Y	H	G	K	L	D	R	T	I	A	E	E	R	L	R	Q	A	G	K	.	S	G	S	Y	L	I	R	E	S	D	R	R	P	G	S	F	V	L	S	F	L	S	Q	M	N	V	V	N	H	F	R	I	I	A	M	C	G	D	Y	Y	I	.	.	G	G	R	R	F	S	S	L	S	D	L	I	G	Y	Y	S
Query Conservation																						.																																										.	.
Alig confidence																						.																						.																				.	.
Template Conservation																																												.
Template Sequence		F	F	F	G	N	I	T	R	E	E	A	E	D	Y	L	V	Q	G	G	M	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	.	H	G	R	K	A	H	H	Y	T	I	E	R	E	L	N	G	T	Y	A	I	A	G	G	R	T	H	A	S	P	A	D	L	C	H	Y	H	S
Template Known Secondary structure		T			S	S												T	T	T			T	T								S	S	S	T	T								.		S	S	S										T	T	T					T	T	S			B	S	S									T
Template Predicted Secondary structure																																												.
Template SS confidence
		15	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.		.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.
		258	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	V	S	C	L	L	K	G	E	K	L	L	Y	P	V	A	P	P	E	P	V	E	D	R	R	R	V	R	A	I	L	P	Y	T	K	V	P	D	T	D	E	I	S	F	L	K	G	D	M	F	I	V	H	N	E	L	E	D	G	W	M	W	V	T	N	L	R	T	D	E	Q	G	L	I	V	E	D	L	V	E
Query Conservation
Alig confidence																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	K	T	P	Q	L
Template Known Secondary structure		T			T	T	S	S	S				S	B					T	T			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		94	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.																																																						.	.	.	.	.	120
		338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.		370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Predicted Secondary structure																																		.																																															.
Query SS confidence																																		.																																															.
Query Sequence		E	V	G	R	E	E	D	P	H	E	G	K	I	W	F	H	G	K	I	S	K	Q	E	A	Y	N	L	L	M	T	V	G	.	Q	V	C	S	F	L	V	R	P	S	D	N	T	P	G	D	Y	S	L	Y	F	R	T	N	E	N	I	Q	R	F	K	I	C	P	T	P	N	N	Q	F	M	M	G	G	R	Y	.
Query Conservation																																		.																																															.
Alig confidence																																		.											.																																				.
Template Conservation																																													.
Template Sequence		E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	.	D	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K
Template Known Secondary structure								T	S	G	G	G		T	T																S	S				T	T								.	S	S	S	S									T	T											T	T	S					T	T	S
Template Predicted Secondary structure																																													.
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.		.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
		416	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	N	S	I	G	D	I	I	D	H	Y	R	K	E	Q	I	V	E	G	Y	Y	L	K	E	P	V	P	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K
Template Known Secondary structure		B	S										T	T			T	T	S	S	S				S	B
Template Predicted Secondary structure
Template SS confidence
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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