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Job DescriptionP19174
Confidence100.00%DateWed May 9 17:43:44 BST 2012
Rank5Aligned Residues292
% Identity54%Templated2zkmx4
SCOP infoTIM beta/alpha-barrel PLC-like phosphodiesterases Mammalian PLC
Resolution1.62

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   319320.........330.........340.........350.........360.........370.. .......380.........390......
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Query Sequence  PDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGP. . DGMPVIYHGHTLTTKIKFSDVLHT
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Template Sequence  HD. MTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEA
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S
GGG
BBSSTTBSS
SSSS
B
TTT




TT

S


TTSS


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   312. ......320.........330.........340.........350.........360.........370.........380.........390
 
   397..400.........410....... ..420.........430.........440........ .450.........460.........470.
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Query Sequence  IKEHAFVASEYPVILSIEDHC. SIAQQRNMAQYFKKVLGDTLLTKPVEISADG. . . . LPSPNQLKRKILIKHKKLAEGSA
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Template Sequence  IAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNN. . . .
Template Known Secondary structure  TTSS

S




GGGB

S

TTS
SSTT




TTTTTT





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   391........400.........410.........420.........430.........440.........450.........460......
 
   472.......480.........490.........500.........510.........520.........530.........540.........550.
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Query Sequence  YEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSSSTELHSNEKWF
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   552.......560.........570.........580.........590.........600.........610.........620.........630.
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Query Sequence  HGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDS
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   632.......640.........650.........660.........670.........680.........690.........700.........710.
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Query Sequence  LYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGK
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   712.......720.........730.........740.........750.........760.........770.........780.........790.
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Query Sequence  IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPT
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   792.......800.........810.........820.........830.........840.........850.........860.........870.
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Query Sequence  FKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDL
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   872.......880.........890.........900.........910.........920.........930.........940.........950.
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Query Sequence  LRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIAL
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Template Conservation  ........................................................                        
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LDEEEIKKMQSDEGTAGLEVTAYE
Template Known Secondary structure  ........................................................
STTGGGGG




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   517..520.........530.........540
 
   952.......960.........970.........980.........990.........1000.........1010.........1020.........1030.
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Query Sequence  ELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWIC
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Template Sequence  EMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLL. SKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNA
Template Known Secondary structure  TT
SS





T
TT.SS

TT
TT




ST
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   541........550.........560.........570.........580. ........590.........600.........610.........
 
   1032.......1040.........1050.........1060.........1070..
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Query Sequence  GSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDE
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Template Sequence  GCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRP
Template Known Secondary structure  T
S
B
TT

STTTGGG
S

GGGT

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   620.........630.........640.........650.........660
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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