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Job DescriptionP19174
Confidence100.00%DateWed May 9 17:43:44 BST 2012
Rank4Aligned Residues555
% Identity44%Templatec1djyB_
PDB info PDB header:lipid degradationChain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   170.........180.........190.........200.........210.........220.........230.........240.........
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Query Sequence  DRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRV
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Template Sequence  NKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETFYKML. . TQRAEIDRAFEE. . . . . . . AAGSAETL
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TT



T
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   158.160.........170.........180.........190.........200........ .210.........220 ........
 
   250.........260.........270.........280.........290.........300.........310.........320.........
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Query Sequence  SLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHY
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Template Sequence  SVERLVTFLQHQQREE. EAGPALALSLIERY. EPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQD. MDQPLSHY
Template Known Secondary structure  TS

S.S
S.


TT
STTTBSB
GGGGS

S
.TTS
GGG
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   229230.........240.... .....250........ .260.........270.........280.........290....... ..300.....
 
   330.........340.........350.........360.........370.........380.........390.........400.........
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Query Sequence  WISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPV
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Template Conservation   
 






 
 

   

   
  

  







 


   



 

 
 
  
 
  
   
   

  
 


Template Sequence  LVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPV
Template Known Secondary structure  SSTTBSS
SSS

B
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GGG



TTS



TTTS
SS
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   306...310.........320.........330.........340.........350.........360.........370.........380.....
 
   410.........420.........430.........440.........450.........460.........470.........480.........
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Query Sequence  ILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNS
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Template Sequence  ILSLENHCSLEQQRVMARHLRAILGPILLDQPLDGVTTSLPSPEQLKGKILLKGKKL. . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 

TTSB

S

SS

SS


TTTTTT



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   386...390.........400.........410.........420.........430.........440..
 
   490.........500.........510.........520.........530.........540.........550.........560.........
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Query Sequence  IKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLL
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   570.........580.........590.........600.........610.........620.........630.........640.........
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Query Sequence  TEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEF
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   650.........660.........670.........680.........690.........700.........710.........720.........
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Query Sequence  EMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNS
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   730.........740.........750.........760.........770.........780.........790.........800.........
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Query Sequence  EFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDE
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   810.........820.........830.........840.........850.........860.........870.........880.........
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Query Sequence  LTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEG
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   890.........900.........910.........920.........930.........940.........950.........960.........
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Query Sequence  KNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEK
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Template Conservation  ....................................................          


 
             
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GGLDKLKLVPELSDMIIYCKSVHFGGFS
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TTT

TT

S





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   443......450.........460.........470
 
   970. ........980.........990.........1000.........1010.........1020.........1030.........1040........
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Query Sequence  IG. TERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQ
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Template Sequence  SPGTSGQAFYEMASFSESRALRLL. QESGNGFVRHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMD
Template Known Secondary structure 
SSS
S

TT.S


TT
TT




TTT


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S
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   509510.........520.........530.. .......540.........550.........560.........570.........580.......
 
   10491050.........1060.........1070... ......1080.........1090.........1100...... ...1110.........1120...
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Query Sequence  MNQALFMTGRHCGYVLQPSTMRDEA. . FDPFDKSSLRGLEPCAISIEVLGARHLPKNGRG. . . IVCPFVEIEVAGAEYDS
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Template Sequence  VYLGCFQDNGGCGYVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEIHGVGRDT
Template Known Secondary structure  TTSGGG
S

GGGS
TT



TTS

SSTT







S

SS



SSGGG
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   588.590.........600.........610.........620.........630.........640.........650.........660.......
 
   1124.....1130.........1140.........1150.........1160.........1170.........1180.........1190.........1200...
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Query Sequence  TKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELA
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Template Sequence  GSRQTAVITNNGFNPRWD. MEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSKNGDQHPSA
Template Known Secondary structure 



TT
SSS
.S
GGG


TTS

GGGB


TTS
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   668.670.........680..... ....690.........700.........710.........720.........730.........740......
 
   1204.....1210...
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Query Sequence  SLLIKIDIFP
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Template Conservation   
 
     
Template Sequence  TLFVKISIQD
Template Known Secondary structure 
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   747..750......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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