Phyre 2 Results for P19174

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Email | l.a.kelley@imperial.ac.uk
Description | P19174
Date | Wed May 9 17:43:44 BST 2012
Unique Job ID | 1975ec919504b475

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c3ohmB_
Top template information
PDB header:signaling protein / hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
Confidence and coverage
Confidence: | 100.0% | Coverage: | 56%
717 residues ( 56% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | A | G | A | A | S | P | C | A | N | G | C | G | P | G | A | P | S | D | A | E | V | L | H | L | C | R | S | L | E | V | G | T | V | M | T | L | F | Y | S | K | K | S | Q | R | P | E | R | K | T | F | Q | V | K | L | E | T | R | Q | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | T | W | S | R | G | A | D | K | I | E | G | A | I | D | I | R | E | I | K | E | I | R | P | G | K | T | S | R | D | F | D | R | Y | Q | E | D | P | A | F | R | P | D | Q | S | H | C | F | V | I | L | Y | G | M | E | F | R | L | K | T | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | S | L | Q | A | T | S | E | D | E | V | N | M | W | I | K | G | L | T | W | L | M | E | D | T | L | Q | A | P | T | P | L | Q | I | E | R | W | L | R | K | Q | F | Y | S | V | D | R | N | R | E | D | R | I | S | A | K | D | L | K | N | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | L | S | Q | V | N | Y | R | V | P | N | M | R | F | L | R | E | R | L | T | D | L | E | Q | R | S | G | D | I | T | Y | G | Q | F | A | Q | L | Y | R | S | L | M | Y | S | A | Q | K | T | M | D | L | P | F | L | E | A | S | T | L | R | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | G | E | R | P | E | L | C | R | V | S | L | P | E | F | Q | Q | F | L | L | D | Y | Q | G | E | L | W | A | V | D | R | L | Q | V | Q | E | F | M | L | S | F | L | R | D | P | L | R | E | I | E | E | P | Y | F | F | L | D | E | F | V | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | F | L | F | S | K | E | N | S | V | W | N | S | Q | L | D | A | V | C | P | D | T | M | N | N | P | L | S | H | Y | W | I | S | S | S | H | N | T | Y | L | T | G | D | Q | F | S | S | E | S | S | L | E | A | Y | A | R | C | L | R | M | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | C | R | C | I | E | L | D | C | W | D | G | P | D | G | M | P | V | I | Y | H | G | H | T | L | T | T | K | I | K | F | S | D | V | L | H | T | I | K | E | H | A | F | V | A | S | E | Y | P | V | I | L | S | I | E | D | H | C | S | I | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | Q | Q | R | N | M | A | Q | Y | F | K | K | V | L | G | D | T | L | L | T | K | P | V | E | I | S | A | D | G | L | P | S | P | N | Q | L | K | R | K | I | L | I | K | H | K | K | L | A | E | G | S | A | Y | E | E | V | P | T | S | M | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | Y | S | E | N | D | I | S | N | S | I | K | N | G | I | L | Y | L | E | D | P | V | N | H | E | W | Y | P | H | Y | F | V | L | T | S | S | K | I | Y | Y | S | E | E | T | S | S | D | Q | G | N | E | D | E | E | E | P | K | E | V | S | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? |  |  |  |  |  | ? |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | S | T | E | L | H | S | N | E | K | W | F | H | G | K | L | G | A | G | R | D | G | R | H | I | A | E | R | L | L | T | E | Y | C | I | E | T | G | A | P | D | G | S | F | L | V | R | E | S | E | T | F | V | G | D | Y | T | L | S | F | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660
Sequence |  | R | N | G | K | V | Q | H | C | R | I | H | S | R | Q | D | A | G | T | P | K | F | F | L | T | D | N | L | V | F | D | S | L | Y | D | L | I | T | H | Y | Q | Q | V | P | L | R | C | N | E | F | E | M | R | L | S | E | P | V | P | Q | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? |  |  |  |  |  |  |  | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720
Sequence |  | N | A | H | E | S | K | E | W | Y | H | A | S | L | T | R | A | Q | A | E | H | M | L | M | R | V | P | R | D | G | A | F | L | V | R | K | R | N | E | P | N | S | Y | A | I | S | F | R | A | E | G | K | I | K | H | C | R | V | Q | Q | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780
Sequence |  | G | Q | T | V | M | L | G | N | S | E | F | D | S | L | V | D | L | I | S | Y | Y | E | K | H | P | L | Y | R | K | M | K | L | R | Y | P | I | N | E | E | A | L | E | K | I | G | T | A | E | P | D | Y | G | A | L | Y | E | G | R | N | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? |  |  |  | ? | ? | ? | ? | ? | ? | ? |  | ? |  | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840
Sequence |  | G | F | Y | V | E | A | N | P | M | P | T | F | K | C | A | V | K | A | L | F | D | Y | K | A | Q | R | E | D | E | L | T | F | I | K | S | A | I | I | Q | N | V | E | K | Q | E | G | G | W | W | R | G | D | Y | G | G | K | K | Q | L | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900
Sequence |  | F | P | S | N | Y | V | E | E | M | V | N | P | V | A | L | E | P | E | R | E | H | L | D | E | N | S | P | L | G | D | L | L | R | G | V | L | D | V | P | A | C | Q | I | A | I | R | P | E | G | K | N | N | R | L | F | V | F | S | I | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? | ? |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960
Sequence |  | M | A | S | V | A | H | W | S | L | D | V | A | A | D | S | Q | E | E | L | Q | D | W | V | K | K | I | R | E | V | A | Q | T | A | D | A | R | L | T | E | G | K | I | M | E | R | R | K | K | I | A | L | E | L | S | E | L | V | V | Y | C
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020
Sequence |  | R | P | V | P | F | D | E | E | K | I | G | T | E | R | A | C | Y | R | D | M | S | S | F | P | E | T | K | A | E | K | Y | V | N | K | A | K | G | K | K | F | L | Q | Y | N | R | L | Q | L | S | R | I | Y | P | K | G | Q | R | L | D | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080
Sequence |  | S | N | Y | D | P | L | P | M | W | I | C | G | S | Q | L | V | A | L | N | F | Q | T | P | D | K | P | M | Q | M | N | Q | A | L | F | M | T | G | R | H | C | G | Y | V | L | Q | P | S | T | M | R | D | E | A | F | D | P | F | D | K | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  | ? |  | ? |  |  | ? | ? | ? |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140
Sequence |  | S | L | R | G | L | E | P | C | A | I | S | I | E | V | L | G | A | R | H | L | P | K | N | G | R | G | I | V | C | P | F | V | E | I | E | V | A | G | A | E | Y | D | S | T | K | Q | K | T | E | F | V | V | D | N | G | L | N | P | V | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200
Sequence |  | P | A | K | P | F | H | F | Q | I | S | N | P | E | F | A | F | L | R | F | V | V | Y | E | E | D | M | F | S | D | Q | N | F | L | A | Q | A | T | F | P | V | K | G | L | K | T | G | Y | R | A | V | P | L | K | N | N | Y | S | E | D | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260
Sequence |  | E | L | A | S | L | L | I | K | I | D | I | F | P | A | K | E | N | G | D | L | S | P | F | S | G | T | S | L | R | E | R | G | S | D | A | S | G | Q | L | F | H | G | R | A | R | E | G | S | F | E | S | R | Y | Q | Q | P | F | E | D | F
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290
Sequence |  | R | I | S | Q | E | H | L | A | D | H | F | D | S | R | E | R | R | A | P | R | R | T | R | V | N | G | D | N | R | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c3ohmB_ |

### PDB 3ohm chain B

Region: 25 - 1238
Aligned: 717
Modelled: 742
Confidence: 100.0%
Identity: 34%
PDB header:signaling protein / hydrolase
Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3

Phyre2
2 |
| c3qr0A_ |

### PDB 3qr0 chain A

Region: 25 - 1237
Aligned: 732
Modelled: 757
Confidence: 100.0%
Identity: 34%
PDB header:hydrolase
Chain: A: PDB Molecule:phospholipase c-beta (plc-beta);
PDBTitle: crystal structure of s. officinalis plc21

Phyre2
3 |
| c2fjuB_ |

### PDB 2fju chain B

Region: 25 - 1213
Aligned: 673
Modelled: 702
Confidence: 100.0%
Identity: 36%
PDB header:signaling protein,apoptosis/hydrolase
Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: activated rac1 bound to its effector phospholipase c beta 2

Phyre2
4 |
| c1djyB_ |

### PDB 1djy chain B

Region: 170 - 1213
Aligned: 555
Modelled: 569
Confidence: 100.0%
Identity: 44%
PDB header:lipid degradation
Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c,
PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate

Phyre2
5 |
| d2zkmx4 |

### PDB 2zkm chain X domain 4

Region: 319 - 1072
Aligned: 292
Modelled: 294
Confidence: 100.0%
Identity: 54%
Fold: TIM beta/alpha-barrel
Superfamily: PLC-like phosphodiesterases
Family: Mammalian PLC

Phyre2
6 |
| d1qasa3 |

### PDB 1qas chain A domain 3

Region: 323 - 1076
Aligned: 274
Modelled: 275
Confidence: 100.0%
Identity: 62%
Fold: TIM beta/alpha-barrel
Superfamily: PLC-like phosphodiesterases
Family: Mammalian PLC

Phyre2
7 |
| c3gqiB_ |

### PDB 3gqi chain B

Region: 545 - 770
Aligned: 226
Modelled: 226
Confidence: 100.0%
Identity: 100%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates

Phyre2
8 |
| c2b3oA_ |

### PDB 2b3o chain A

Region: 549 - 762
Aligned: 199
Modelled: 210
Confidence: 100.0%
Identity: 30%
PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1

Phyre2
9 |
| c3ps5A_ |

### PDB 3ps5 chain A

Region: 549 - 762
Aligned: 199
Modelled: 214
Confidence: 100.0%
Identity: 31%
PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1

Phyre2
10 |
| c2shpA_ |

### PDB 2shp chain A

Region: 547 - 762
Aligned: 201
Modelled: 216
Confidence: 100.0%
Identity: 32%
PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2

Phyre2
11 |
| d2zkmx2 |

### PDB 2zkm chain X domain 2

Region: 1089 - 1213
Aligned: 118
Modelled: 125
Confidence: 100.0%
Identity: 31%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2
12 |
| d1qasa2 |

### PDB 1qas chain A domain 2

Region: 1087 - 1213
Aligned: 124
Modelled: 127
Confidence: 100.0%
Identity: 34%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2
13 |
| c2oq1A_ |

### PDB 2oq1 chain A

Region: 549 - 758
Aligned: 195
Modelled: 205
Confidence: 99.9%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2
14 |
| c2lqnA_ |

### PDB 2lqn chain A

Region: 538 - 858
Aligned: 302
Modelled: 310
Confidence: 99.9%
Identity: 20%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2
15 |
| c2ozoA_ |

### PDB 2ozo chain A

Region: 549 - 778
Aligned: 215
Modelled: 225
Confidence: 99.9%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2
16 |
| c1a81E_ |

### PDB 1a81 chain E

Region: 547 - 758
Aligned: 200
Modelled: 208
Confidence: 99.9%
Identity: 27%
PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam

Phyre2
17 |
| c2eyzA_ |

### PDB 2eyz chain A

Region: 538 - 856
Aligned: 288
Modelled: 300
Confidence: 99.9%
Identity: 21%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2
18 |
| d2zkmx3 |

### PDB 2zkm chain X domain 3

Region: 25 - 148
Aligned: 122
Modelled: 124
Confidence: 99.9%
Identity: 16%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Pleckstrin-homology domain (PH domain)

Phyre2
19 |
| c2fjlA_ |

### PDB 2fjl chain A

Region: 489 - 933
Aligned: 150
Modelled: 150
Confidence: 99.9%
Identity: 100%
PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the split ph domain in phospholipase2 c-gamma1

Phyre2
20 |
| d2zkmx1 |

### PDB 2zkm chain X domain 1

Region: 153 - 318
Aligned: 128
Modelled: 150
Confidence: 99.9%
Identity: 20%
Fold: EF Hand-like
Superfamily: EF-hand
Family: EF-hand modules in multidomain proteins

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c3ohmB_ |
|  | 100.0 | 34 | PDB header:signaling protein / hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
2 | c3qr0A_ |
|  | 100.0 | 34 | PDB header:hydrolase Chain: A: PDB Molecule:phospholipase c-beta (plc-beta); PDBTitle: crystal structure of s. officinalis plc21
3 | c2fjuB_ |
|  | 100.0 | 36 | PDB header:signaling protein,apoptosis/hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: activated rac1 bound to its effector phospholipase c beta 2
4 | c1djyB_ |
|  | 100.0 | 44 | PDB header:lipid degradation Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
5 | d2zkmx4 |
|  | 100.0 | 54 | Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Mammalian PLC
6 | d1qasa3 |
|  | 100.0 | 62 | Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Mammalian PLC
7 | c3gqiB_ |
|  | 100.0 | 100 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:phospholipase c-gamma-1; PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
8 | c2b3oA_ |
|  | 100.0 | 30 | PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
9 | c3ps5A_ |
|  | 100.0 | 31 | PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6; PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
10 | c2shpA_ |
|  | 100.0 | 32 | PDB header:tyrosine phosphatase Chain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2
11 | d2zkmx2 |
|  | 100.0 | 31 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
12 | d1qasa2 |
|  | 100.0 | 34 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
13 | c2oq1A_ |
|  | 99.9 | 29 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
14 | c2lqnA_ |
|  | 99.9 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl
15 | c2ozoA_ |
|  | 99.9 | 27 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
16 | c1a81E_ |
|  | 99.9 | 27 | PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
17 | c2eyzA_ |
|  | 99.9 | 21 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii
18 | d2zkmx3 |
|  | 99.9 | 16 | Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain)
19 | c2fjlA_ |
|  | 99.9 | 100 | PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the split ph domain in phospholipase2 c-gamma1
20 | d2zkmx1 |
|  | 99.9 | 20 | Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins
21 | d1djxb1 |
| not modelled | 99.8 | 16 | Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins
22 | c3h4wA_ |
| not modelled | 99.8 | 23 | PDB header:hydrolase Chain: A: PDB Molecule:phosphatidylinositol-specific phospholipase c1; PDBTitle: structure of a ca+2 dependent phosphatidylinositol-specific2 phospholipase c (pi-plc) enzyme from streptomyces antibioticus
23 | c2eyyA_ |
| not modelled | 99.8 | 26 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i
24 | d1maia_ |
| not modelled | 99.8 | 19 | Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain)
25 | d1qasa1 |
| not modelled | 99.8 | 18 | Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins
26 | c2dvjA_ |
| not modelled | 99.7 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii
27 | c3qwxX_ |
| not modelled | 99.7 | 22 | PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174
28 | c3qwyA_ |
| not modelled | 99.7 | 22 | PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2
29 | c3or8A_ |
| not modelled | 99.6 | 18 | PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
30 | c2vszA_ |
| not modelled | 99.6 | 19 | PDB header:apoptosis Chain: A: PDB Molecule:engulfment and cell motility protein 1; PDBTitle: crystal structure of the elmo1 ph domain
31 | c2eobA_ |
| not modelled | 99.6 | 58 | PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
32 | c2xp1A_ |
| not modelled | 99.6 | 17 | PDB header:transcription Chain: A: PDB Molecule:spt6; PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
33 | c2gsbA_ |
| not modelled | 99.5 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
34 | d2nq3a1 |
| not modelled | 99.5 | 25 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
35 | c2nq3A_ |
| not modelled | 99.5 | 25 | PDB header:ligase Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase; PDBTitle: crystal structure of the c2 domain of human itchy homolog2 e3 ubiquitin protein ligase
36 | c2dmhA_ |
| not modelled | 99.4 | 24 | PDB header:lipid binding protein Chain: A: PDB Molecule:myoferlin; PDBTitle: solution structure of the first c2 domain of human myoferlin
37 | d2r83a1 |
| not modelled | 99.4 | 20 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
38 | c2q3xA_ |
| not modelled | 99.4 | 19 | PDB header:transport protein Chain: A: PDB Molecule:regulating synaptic membrane exocytosis protein 1; PDBTitle: the rim1alpha c2b domain
39 | d2fcia1 |
| not modelled | 99.4 | 97 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
40 | d1rlwa_ |
| not modelled | 99.4 | 20 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
41 | d1gmia_ |
| not modelled | 99.4 | 20 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
42 | c2dx0B_ |
| not modelled | 99.4 | 66 | PDB header:hydrolase Chain: B: PDB Molecule:phospholipase c, gamma 2; PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
43 | c3l9bA_ |
| not modelled | 99.4 | 8 | PDB header:membrane protein Chain: A: PDB Molecule:otoferlin; PDBTitle: crystal structure of rat otoferlin c2a
44 | c3m7fB_ |
| not modelled | 99.4 | 19 | PDB header:signaling protein/ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex
45 | c2chdA_ |
| not modelled | 99.4 | 25 | PDB header:protein transport Chain: A: PDB Molecule:rabphilin-3a; PDBTitle: crystal structure of the c2a domain of rabphilin-3a
46 | c3nsjA_ |
| not modelled | 99.4 | 17 | PDB header:immune system Chain: A: PDB Molecule:perforin-1; PDBTitle: the x-ray crystal structure of lymphocyte perforin
47 | c3kwtA_ |
| not modelled | 99.3 | 29 | PDB header:metal binding protein Chain: A: PDB Molecule:munc13-1; PDBTitle: munc13-1 c2b-domain, calcium-free
48 | c3fbkB_ |
| not modelled | 99.3 | 21 | PDB header:signaling protein Chain: B: PDB Molecule:regulator of g-protein signaling 3; PDBTitle: crystal structure of the c2 domain of the human regulator2 of g-protein signaling 3 isoform 6 (rgp3), northeast3 structural genomics consortium target hr5550a
49 | c2y3aB_ |
| not modelled | 99.3 | 32 | PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
50 | c2eo6A_ |
| not modelled | 99.3 | 26 | PDB header:signaling protein Chain: A: PDB Molecule:b-cell linker protein; PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
51 | c3hizB_ |
| not modelled | 99.3 | 27 | PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
52 | d1dsya_ |
| not modelled | 99.3 | 24 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
53 | c2fk9A_ |
| not modelled | 99.3 | 20 | PDB header:transferase Chain: A: PDB Molecule:protein kinase c, eta type; PDBTitle: human protein kinase c, eta
54 | d1csya_ |
| not modelled | 99.3 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
55 | c3a98B_ |
| not modelled | 99.3 | 18 | PDB header:signaling protein Chain: B: PDB Molecule:engulfment and cell motility protein 1; PDBTitle: crystal structure of the complex of the interacting regions of dock22 and elmo1
56 | d3c7ia1 |
| not modelled | 99.3 | 34 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
57 | d1a25a_ |
| not modelled | 99.3 | 23 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
58 | d1a81a1 |
| not modelled | 99.2 | 21 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
59 | c2dlzA_ |
| not modelled | 99.2 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the sh2 domain of human protein vav-2
60 | d2qmsa1 |
| not modelled | 99.2 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
61 | d2izva2 |
| not modelled | 99.2 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
62 | d1a81e2 |
| not modelled | 99.2 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
63 | d2oq1a1 |
| not modelled | 99.2 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
64 | c3jzyA_ |
| not modelled | 99.2 | 24 | PDB header:endocytosis Chain: A: PDB Molecule:intersectin 2; PDBTitle: crystal structure of human intersectin 2 c2 domain
65 | d1ugka_ |
| not modelled | 99.2 | 19 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
66 | d2oq1a2 |
| not modelled | 99.2 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
67 | c2z0uB_ |
| not modelled | 99.2 | 16 | PDB header:lipid binding protein Chain: B: PDB Molecule:ww domain-containing protein 1; PDBTitle: crystal structure of c2 domain of kibra protein
68 | c2nsqA_ |
| not modelled | 99.2 | 23 | PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4-like protein; PDBTitle: crystal structure of the c2 domain of the human e3 ubiquitin-protein2 ligase nedd4-like protein
69 | d1rjaa_ |
| not modelled | 99.2 | 34 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
70 | c2enpA_ |
| not modelled | 99.2 | 23 | PDB header:transport protein Chain: A: PDB Molecule:b/k protein; PDBTitle: solution structure of the first c2 domain from human b/k2 protein
71 | c1dqvA_ |
| not modelled | 99.2 | 26 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:synaptotagmin iii; PDBTitle: crystal structure of synaptotagmin iii c2a/c2b
72 | d1pica_ |
| not modelled | 99.2 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
73 | d1fhsa_ |
| not modelled | 99.2 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
74 | c2jqzA_ |
| not modelled | 99.2 | 21 | PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2; PDBTitle: solution structure of the c2 domain of human smurf2
75 | d1a81e1 |
| not modelled | 99.2 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
76 | d1nrva_ |
| not modelled | 99.2 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
77 | c3evrA_ |
| not modelled | 99.2 | 14 | PDB header:signaling protein Chain: A: PDB Molecule:myosin light chain kinase, green fluorescent PDBTitle: crystal structure of calcium bound monomeric gcamp2
78 | d1v27a_ |
| not modelled | 99.2 | 22 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
79 | c2d8kA_ |
| not modelled | 99.2 | 23 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:synaptotagmin vii; PDBTitle: solution structure of the first c2 domain of synaptotagmin2 vii
80 | c2b3rA_ |
| not modelled | 99.2 | 17 | PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol-4-phosphate 3-kinase c2 domain- PDBTitle: crystal structure of the c2 domain of class ii phosphatidylinositide2 3-kinase c2
81 | d1wfma_ |
| not modelled | 99.2 | 19 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
82 | c2crhA_ |
| not modelled | 99.2 | 26 | PDB header:signaling protein Chain: A: PDB Molecule:vav proto-oncogene; PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
83 | d2ep6a1 |
| not modelled | 99.1 | 27 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
84 | c2ci8A_ |
| not modelled | 99.1 | 33 | PDB header:translation Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
85 | c2el8A_ |
| not modelled | 99.1 | 18 | PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 2; PDBTitle: solution structure of the human stap2 sh2 domain
86 | c2ysxA_ |
| not modelled | 99.1 | 32 | PDB header:signaling protein Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase PDBTitle: solution structure of the human ship sh2 domain
87 | d1luia_ |
| not modelled | 99.1 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
88 | d1rsya_ |
| not modelled | 99.1 | 24 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
89 | c2dlyA_ |
| not modelled | 99.1 | 23 | PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
90 | c2r83B_ |
| not modelled | 99.1 | 21 | PDB header:endocytosis, exocytosis Chain: B: PDB Molecule:synaptotagmin-1; PDBTitle: crystal structure analysis of human synaptotagmin 1 c2a-c2b
91 | d1a81a2 |
| not modelled | 99.1 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
92 | c1ka6A_ |
| not modelled | 99.1 | 25 | PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py
93 | d1bdya_ |
| not modelled | 99.1 | 17 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
94 | d1wfja_ |
| not modelled | 99.1 | 16 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
95 | d1xa6a2 |
| not modelled | 99.1 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
96 | d2cs0a1 |
| not modelled | 99.1 | 36 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
97 | d1qcfa2 |
| not modelled | 99.1 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
98 | d1ayaa_ |
| not modelled | 99.1 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
99 | c2fo0A_ |
| not modelled | 99.1 | 27 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
100 | d2shpa2 |
| not modelled | 99.1 | 35 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
101 | d1opka2 |
| not modelled | 99.1 | 37 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
102 | d2bwqa1 |
| not modelled | 99.1 | 23 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
103 | c1y57A_ |
| not modelled | 99.1 | 29 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
104 | c1oplA_ |
| not modelled | 99.1 | 26 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
105 | c2dcrA_ |
| not modelled | 99.1 | 23 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
106 | d2eyva1 |
| not modelled | 99.1 | 39 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
107 | c2eo3A_ |
| not modelled | 99.1 | 26 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
108 | d1blja_ |
| not modelled | 99.1 | 23 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
109 | d1i3za_ |
| not modelled | 99.1 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
110 | d1bkla_ |
| not modelled | 99.1 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
111 | d1f2fa_ |
| not modelled | 99.0 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
112 | d1jyra_ |
| not modelled | 99.0 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
113 | c2ge9A_ |
| not modelled | 99.0 | 28 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
114 | d1d4ta_ |
| not modelled | 99.0 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
115 | c2dmgA_ |
| not modelled | 99.0 | 20 | PDB header:lipid binding protein Chain: A: PDB Molecule:kiaa1228 protein; PDBTitle: solution structure of the third c2 domain of kiaa12282 protein
116 | c1x6cA_ |
| not modelled | 99.0 | 32 | PDB header:signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
117 | d2cjsa1 |
| not modelled | 99.0 | 20 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
118 | d1mila_ |
| not modelled | 99.0 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
119 | c2cr4A_ |
| not modelled | 99.0 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain-binding protein 2; PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
120 | c2ablA_ |
| not modelled | 99.0 | 31 | PDB header:transferase Chain: A: PDB Molecule:abl tyrosine kinase; PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase

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