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Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank186Aligned Residues230
% Identity23%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   264.....270.........280.........290.. .......300.........310.........320.........330...... ...340.
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Query Sequence  WEIPRESLQLIKRLGNGQFGEVWMGTWNG. NTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE. PIYIV
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSRHPFLTALKYSFQTHDRLCFV
Template Known Secondary structure  T


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   112.......120.........130.........140.........150. ........160.........170.........180.....
 
   342.......350.........360.........370.........380... ......390.........400.........410.........420
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Query Sequence  TEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER. MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
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Template Sequence  MEYANGGELFFHLSRERV. . FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLC. . . . . . . .
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   227..230.........240.... .....250.........260.........270.........280.........290......
 
   421........430.........440.........450.........460.........470.........480.........490.........500
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Query Sequence  TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI
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Template Sequence  . . . . . . . KEPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILME. EIRFPRTLGPEAKSLLS
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   297..300.........310.........320.........330 .........340.........350 .........360.......
 
   501........510 ........
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Query Sequence  HCWKKDPEER. . . . . PTFEYLQS
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Template Sequence  GLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
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   382.......390.........400....
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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