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Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank165Aligned Residues250
% Identity27%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   269270.........280.........290.........300.........310.........320.........330... ......340...
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Query Sequence  ESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV. . . . . SEEPIYIVTE
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITH
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240.........250.........260.........270.........280....
 
   344.....350.........360.........370.........380...... ...390.........400.........410.....
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Query Sequence  YMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNY. . . . . . . . IHRDLRSANILVGNGLICKIADFGLARLI
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Template Sequence  YHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMH
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TT
B

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B
STT
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SGGG
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   285....290......... 300.........310.........320.........330.........340.........350.........360.
 
   416 ...420.........430.........440.. .......450.........460.........470..
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Query Sequence  E. . . DNEYTARQGAKFPIKWTAPEAALYGR. . . . . . FTIKSDVWSFGILLTELVTKGRVPYPGMNN. . . . . . . . . . . . . .
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Template Sequence  SQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPS
Template Known Secondary structure  TTTT








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BTTB





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   362.......370.........380.........390.........400.........410...... ...420.........430.........440
 
   473......480.........490 .........500.........510.........520...
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Query Sequence  . REVLEQVERGYRMPCPQD. . . . . . CPISLHELMIHCWKKDPEERPTFEYLQSFLEDY
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Template Sequence  FEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   441........450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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