Return to main results Retrieve Phyre Job Id

Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank60Aligned Residues262
% Identity33%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   262.......270.........280.........290.. .......300.. .......310.........320.........330.....
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Query Sequence  DVWEIPRESLQLIKRLGNGQFGEVWMGTWNG. . . . . NTKVAIKTLK. PGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSE
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCY.
Template Known Secondary structure 
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   840.........850.........860.........870.........880.........890.........900.........910........
 
   336...340.........350.........360.........370.........380.........390.........400.........410.....
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Query Sequence  EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI
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Template Sequence  SNLKLIMEYLPYGSLRDYLQKHKER. IDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVL
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TT
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   919920.........930.........940... ......950.........960.........970.........980.........990.......
 
   416...420.........430.........440.........450.........460......... 470.........
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Query Sequence  EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG. . . . . . . . . . . . . . . . MNNREVLEQV
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Template Sequence  PQDKEKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
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   1002.......1010.........1020.........1030.........1040....... ..1050.........1060.........1070.........1080
 
   480.........490.........500.........510.........520......
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Query Sequence  ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTA
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Template Sequence  KNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDQ
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TT

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   1083......1090.........1100.........1110.........1120.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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