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Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank187Aligned Residues253
% Identity23%Templatec3fmeA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6; PDBTitle: crystal structure of human mitogen-activated protein kinase kinase 62 (mek6) activated mutant (s207d, t211d)
Resolution2.26 Å

  Insertion relative to template
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  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   265....270.........280.........290..... ....300.........310.........320.........330...... ...340..
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Query Sequence  EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK. VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE. PIYIVT
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Template Sequence  EVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICM
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   47..50.........60.........70.........80.........90.........100.........110.........120......
 
   343......350.... .....360.........370.........380.. .......390.........400.........410.........420
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Query Sequence  EYMNKGSLLDFL. KDGEGRALKLPNLVDMAAQVAAGMAYIE. RMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
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Template Sequence  ELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFAGCKP. . . . . .
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   130.........140.........150.........160.........170.........180.........190.........200...
 
   421........430.........440.. .......450.........460.........470. ........480.........490......
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Query Sequence  TARQGAKFPIKWTAPEAALYGR. . FTIKSDVWSFGILLTELVTKGRVPYPGMN. . NREVLEQVERGYRMPCPQDCPISLH
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Template Sequence  . . . . . . . . . . . YMAPERINPELNQYSVKSDIWSLGITMIELAI. LRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFV
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   219220.........230.........240.........250 .........260.........270.........280......
 
   497..500.........510.........520.........530.......
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Query Sequence  ELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL
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Template Sequence  DFTSQCLKKNSKERPTYPELMQH. . PFFTLHESKGTDVASF
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   289290.........300.........310. ........320.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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