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Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank244Aligned Residues226
% Identity24%Templatec3alnB_
PDB info PDB header:transferaseChain: B: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 4; PDBTitle: crystal structure of human non-phosphorylated mkk4 kinase domain2 complexed with amp-pnp
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   255....260.........270.........280.........290 .........300.........310 .........320.........330
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Query Sequence  DLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTW. NGNTKVAIKTLKPGTMSPES. . . FLEEAQIMKKLKHDKLVQLY
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Template Sequence  KLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFY
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   86...90.........100.........110.........120.........130.........140.........150.........160.....
 
   331 ........340.........350.... .....360.........370.........380.... .....390.........400......
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Query Sequence  A. VVSEEPIYIVTEYMNKGSLLDFL. . KDGEGRALKLPNLVDMAAQVAAGMAYIERM. NYIHRDLRSANILVGNGLICKI
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Template Sequence  GALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKL
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SGGGB
B
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B
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   166...170.........180.........190.........200.........210.........220.........230.........240.....
 
   407..410.........420.........430.........440.........450.........460.........470.........480......
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Query Sequence  ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP
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Template Sequence  CDFGIS. . . . . . . . . . . . . . . . . . . . . . . . . . . GQLYDVRSDVWSLGITLYELAT. GRFPYPDPP. . . . . . . . . . QLSNS
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   246...250. ........260.........270... ......280.. .....
 
   487..490.........500.........510........
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Query Sequence  CPQDCPISLHELMIHCWKKDPEERPTFEYLQS
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Template Sequence  EEREFSPSFINFVNLCLTKDESKRPKYKELLK
Template Known Secondary structure  TT





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   332.......340.........350.........360...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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