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Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank108Aligned Residues256
% Identity24%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   267..270.........280.........290 .........300.. .......310.........320.........330...... ...340
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Query Sequence  PRESLQLIKRLGNGQFGEVWMGTW. NGNTKVAIKTLK. . . . PGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE. PIYI
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYF
Template Known Secondary structure 
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   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
   341........350.........360.........370.........380.........390.........400.........410.........420
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Query Sequence  VTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
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Template Sequence  GLSYAKNGELLKYIRK. . IGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTA. . . . . . . .
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   158.160.........170... ......180.........190.........200.........210.........220.......
 
   421........430.........440.........450.........460.........470.........480.........490.........500
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Query Sequence  TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI
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Template Sequence  . . KVLFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVE
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   228.230.........240.........250.........260...... ...270.........280....... ..290.........300...
 
   501........510........ .520.........530......
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Query Sequence  HCWKKDPEERPTFEYLQS. . . . . . . . FLEDYFTATEPQYQPGEN
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Template Sequence  KLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKL
Template Known Secondary structure  TTS
SSTTSSTTSGGGTTSGGGTT

GGGGGGS




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   315....320.........330.........340.........350........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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